Dimethylallyl pyrophosphate

Template:Chembox IndexlistTemplate:Chembox CompToxTemplate:Chembox Datapage check

Dimethylallyl pyrophosphate

Names
IUPAC name 3-Methyl-2-buten-1-yl trihydrogen diphosphate
Other names Dimethylallyl diphosphate; isoprenyl pyrophosphate; isoprenyl diphosphate
Identifiers
CAS Number	358-72-5 checkY
3D model (JSmol)	Interactive image
ChemSpider	627 checkY
EC Number	Template:Chembox ECNumber/format Template:Chembox ECNumber/format Template:Chembox ECNumber/format Template:Chembox ECNumber/format Template:Chembox ECNumber/format Template:Chembox ECNumber/format
MeSH	3,3-dimethylallyl+pyrophosphate
PubChem CID	647
RTECS number	Template:Chembox RTECS/format Template:Chembox RTECS/format Template:Chembox RTECS/format Template:Chembox RTECS/format Template:Chembox RTECS/format Template:Chembox RTECS/format
InChI InChI=1S/C5H12O7P2/c1-5(2)3-4-11-14(9,10)12-13(6,7)8/h3H,4H2,1-2H3,(H,9,10)(H2,6,7,8) Key: CBIDRCWHNCKSTO-UHFFFAOYSA-N
SMILES CC(=CCOP(=O)(O)OP(=O)(O)O)C
Properties
Chemical formula	C5H12O7P2
Molar mass	246.092 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). checkY verify (what is checkY☒N ?) Infobox references

Dimethylallyl pyrophosphate (DMAPP; or alternatively, dimethylallyl diphosphate (DMADP); also isoprenyl pyrophosphate) is an isoprenoid precursor. It is a product of both the mevalonate pathway and the MEP pathway of isoprenoid precursor biosynthesis. It is an isomer of isopentenyl pyrophosphate (IPP) and exists in virtually all life forms. The enzyme isopentenyl pyrophosphate isomerase catalyzes isomerization between DMAPP and IPP.

In the mevalonate pathway, DMAPP is synthesised from mevalonic acid. In contrast, DMAPP is synthesised from HMBPP in the MEP pathway.

At present, it is believed that there is crossover between the two pathways in organisms that use both pathways to create terpenes and terpenoids, such as in plants, and that DMAPP is the crossover product.

File:Mevalonate pathway.svg

Mevalonate pathway

File:Sterol synthesis.svg

Simplified version of the steroid synthesis pathway with the intermediates isopentenyl pyrophosphate (IPP), dimethylallyl pyrophosphate (DMAPP), geranyl pyrophosphate (GPP) and squalene shown. Some intermediates are omitted.