Pipecuronium bromide

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Pipecuronium bromide
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Clinical data
Trade namesArduan
AHFS/Drugs.comInternational Drug Names
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Identifiers
  • (2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2,16-bis(4,4-dimethylpiperazin-4-ium-1-yl)androstane dibromide
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Chemical and physical data
FormulaC35H62Br2N4O4
Molar mass762.713 g·mol−1
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  • [Br-].[Br-].O=C(O[C@H]6[C@@H](N1CC[N+](C)(C)CC1)C[C@@H]5[C@]6(C)CC[C@H]3[C@H]5CC[C@H]4C[C@H](OC(=O)C)[C@@H](N2CC[N+](CC2)(C)C)C[C@]34C)C
  • InChI=1S/C35H62N4O4.2BrH/c1-24(40)42-32-21-26-9-10-27-28(35(26,4)23-31(32)37-15-19-39(7,8)20-16-37)11-12-34(3)29(27)22-30(33(34)43-25(2)41)36-13-17-38(5,6)18-14-36;;/h26-33H,9-23H2,1-8H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1 checkY
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Pipecuronium (Arduan) is a bisquaternary aminosteroid muscle relaxant[1] which blocks nicotinic acetylcholine receptors[2][3] at the neuromuscular junction. It is also an antagonist of M2 and M3 muscarinic receptors[2] and is the most potent neuromuscular blocking agent of the aminosteroid class.[citation needed]

It is sold under the trade names Arduan and Pycuron.[4]

See also

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content."Pipecuronium Bromide". WHOCC - ATC/DDD Index. M03AC06.
  2. ^ a b Page Module:Citation/CS1/styles.css has no content."Pipecuronium". DrugBank.
  3. ^ Page Module:Citation/CS1/styles.css has no content.Singh H, Jindal DP, Yadav MR, Kumar M (January 1991). "5 Heterosteroids and drug research.". Progress in Medicinal Chemistry. Vol. 28. pp. 233-300 (270). doi:10.1016/S0079-6468(08)70366-7. ISBN 978-0-444-81275-9. PMID 1843548.
  4. ^ Page Module:Citation/CS1/styles.css has no content."Pipecuronium - brand name list from". Drugs.com. Retrieved 2022-09-17.


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