Dyclonine

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Dyclonine
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Clinical data
Trade namesSucrets
AHFS/Drugs.comMonograph
Routes of
administration		Lozenge
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Legal status
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Identifiers
  • 1-(4-butoxyphenyl)-3-(1-piperidyl)propan-1-one
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Chemical and physical data
FormulaC18H27NO2
Molar mass289.419 g·mol−1
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  • O=C(c1ccc(OCCCC)cc1)CCN2CCCCC2
  • InChI=1S/C18H27NO2/c1-2-3-15-21-17-9-7-16(8-10-17)18(20)11-14-19-12-5-4-6-13-19/h7-10H,2-6,11-15H2,1H3 checkY
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Dyclonine (Dyclocaine) is an oral anaesthetic that is the active ingredient of Sucrets, an over-the-counter throat lozenge.[1] It is also found in some varieties of the Cepacol sore throat spray. It is a local anesthetic, used topically as the hydrochloride salt.[2]

History

The product Sucrets was introduced in Baltimore, Maryland, by Sharp & Dohme in 1932.[3]

In 1966 the Federal Trade Commission ordered Merck and Company to discontinue the false claims of germ-killing and pain-relieving properties for its Sucrets and Children's Sucrets throat lozenges.[4] In 1977, it was acquired by Beecham, later merging with SmithKline Beckman in 1989 to form SmithKline Beecham. Also in 1977, Sucrets released a memorable TV commercial starring Harry Goz as a miserable husband who wakes his wife up to remedy his sore throat. The ad ran for many years and helped increase the brand's sales. By 1994 the brand switched from a metal container to a plastic container.[3] SmithKline Beecham, after announcing a merger with GlaxoWellcome to form GlaxoSmithKline, sold the brand in 2000 to Insight Pharmaceuticals. In 2011, Sucrets reintroduced their product back into the familiar tin due to popular demand and nostalgia.

See also

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content.Janice Jorgensen (1994). "Sucrets". Encyclopedia of Consumer Brands: Personal products. St. James Press. ISBN 9781558623378. Retrieved 2011-09-24.
  2. ^ Page Module:Citation/CS1/styles.css has no content.Gargiulo AV, Burns GM, Huck CP (1992). "Dyclonine hydrochloride--a topical agent for managing pain". Illinois Dental Journal. 61 (4): 303–4. PMID 1286862.
  3. ^ a b Page Module:Citation/CS1/styles.css has no content."The Sucrets tin joins the age of plastics". USA Today. July 19, 1994. Archived from the original on 2017-08-22. Retrieved 2011-09-24.
  4. ^ Page Module:Citation/CS1/styles.css has no content."F.T.C. Bids Merck Halt Claims That Lozenges Will Kill Germs". The New York Times. Associated Press. April 19, 1966. Retrieved 2011-09-24.

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