Tandemly arrayed genes
Template:Short description Tandemly arrayed genes (TAGs) are a gene cluster created by tandem duplications,Lua error in package.lua at line 80: module 'Module:Footnotes/anchor_id_list' not found. a process in which one gene is duplicated and the copy is found adjacent to the original.Lua error in package.lua at line 80: module 'Module:Footnotes/anchor_id_list' not found. They serve to encode large numbers of genes at a time.
TAGs represent a large proportion of genes in a genome, including between 14% and 17% of the human, mouse, and rat genomes.Lua error in package.lua at line 80: module 'Module:Footnotes/anchor_id_list' not found. TAG clusters may have as few as two genes, with small clusters predominating, but may consist of hundreds of genes.Lua error in package.lua at line 80: module 'Module:Footnotes/anchor_id_list' not found. An example are tandem clusters of rRNA encoding genes. These genes are transcribed faster than they would be if only a single copy of the gene was available. Additionally, a single RNA gene may not be able to provide enough RNA, but tandem repeats of the gene allow sufficient RNA to be produced. For example, cells in a human embryo contain between five and ten million ribosomes, and cell number doubles within 24 hours. In order to provide the necessary ribosomes, multiple RNA polymerases must consecutively transcribe multiple rRNA genes.[1]
In some species, such as Arabidopsis thaliana and Oryza sativa, most TAGs are the result of unequal chromosomal crossover during genetic recombination.Lua error in package.lua at line 80: module 'Module:Footnotes/anchor_id_list' not found.
See also
Notes
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- ^ Page Module:Citation/CS1/styles.css has no content.Lodish, Harvey; Arnold Berk; Chris Kaiser; Monty Krieger; Anthony Bretscher; Hidde Ploegh; Angelika Amon; Matthew Scott (2013). "Genes, Genomics, and Chromosomes". In Beth McHenry (ed.). Molecular Cell Biology (7 ed.). New York: W.H. Freeman Company. pp. 227–230. ISBN 978-1-4292-3413-9.
References
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- Page Module:Citation/CS1/styles.css has no content.Barker, Michael S.; Baute, Gregory J.; Liu, Shao-Lun (5 March 2012). "Duplications and Turnover in Plant Genomes". In Wendel, Jonathan F.; Greilhuber, Johann; Dolezel, Jaroslav; et al. (eds.). Plant Genome Diversity Volume 1: Plant Genomes, their Residents, and their Evolutionary Dynamics. Plant Genome Diversity. Vol. 1. Springer Science & Business Media. pp. 155–169. doi:10.1007/978-3-7091-1130-7_11. ISBN 978-3-7091-1130-7.
- Page Module:Citation/CS1/styles.css has no content.Pan, Deng; Zhang, Liqing (2008). "Tandemly arrayed genes in vertebrate genomes". International Journal of Genomics. 2008 545269. Hindawi Publishing Corporation. doi:10.1155/2008/545269. PMC 2547482. PMID 18815629.
- Page Module:Citation/CS1/styles.css has no content.Lajoie, Mathieu; Bertrand, Denis; El-Mabrouk, Nadia (16–18 September 2007). "Evolution of tandemly-arrayed genes in multiple species". In Tesler, Glenn; Durand, Dannie (eds.). Comparative Genomics: RECOMB 2007, International Workshop, RECOMB-CG 2007, San Diego, CA, USA, September 16–18, 2007, Proceedings. RECOMB 2007, International Workshop, RECOMB-CG 2007. Lecture Notes in Bioinformatics. Vol. 4751. San Diego: Springer Science & Business Media. pp. 96–107. ISBN 978-3-540-74959-2. ISSN 0302-9743.
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