APOBEC3F

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Template:Short description Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). DNA dC->dU-editing enzyme APOBEC-3F is a protein that in humans is encoded by the APOBEC3F gene.[1][2][3]

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified.[3]

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content.Jarmuz A, Chester A, Bayliss J, Gisbourne J, Dunham I, Scott J, Navaratnam N (Feb 2002). "An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22". Genomics. 79 (3): 285–96. doi:10.1006/geno.2002.6718. PMID 11863358.
  2. ^ Page Module:Citation/CS1/styles.css has no content.Holmes RK, Koning FA, Bishop KN, Malim MH (Jan 2007). "APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G". J Biol Chem. 282 (4): 2587–95. doi:10.1074/jbc.M607298200. PMID 17121840.
  3. ^ a b Page Module:Citation/CS1/styles.css has no content."Entrez Gene: APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F".

Human APOBEC3F is another host factor that blocks human immunodeficiency virus type 1 replication. Zheng YH, Irwin D, Kurosu T, Tokunaga K, Sata T, Peterlin BM. J Virol. 2004 Jun;78(11):6073-6. doi: 10.1128/JVI.78.11.6073-6076.2004.

Further reading

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