C8 complex
From Wikipedia, the free encyclopedia
Complement component 8 is a protein involved in the complement system. It is part of the membrane attack complex (MAC).
A hereditary deficiency of C8 can result in increased susceptibility to Neisseria infections, such as meningitis and gonorrhea.
Page Template:Col-begin/styles.css has no content.
Page Module:Infobox/styles.css has no content.
|
Page Module:Infobox/styles.css has no content.
|
Page Module:Infobox/styles.css has no content.
|
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Structure
C8 is a heterotrimer; it consists of three different subunits. These are called C8 alpha, beta and gamma chains, encoded by the genes C8A, C8B and C8G respectively.
References
Page Template:Reflist/styles.css has no content.
- ^ Template:PDB; Page Module:Citation/CS1/styles.css has no content.Lovelace LL, Cooper CL, Sodetz JM, Lebioda L (May 2011). "Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement". The Journal of Biological Chemistry. 286 (20): 17585–92. doi:10.1074/jbc.M111.219766. PMC 3093833. PMID 21454577.
External links
- Complement+C8 at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Lua error in package.lua at line 80: module 'Module:Navbox/configuration' not found.
