Corrin
Script error: No such module "other uses". Page Template:Chembox/styles.css has no content.
Template:Chembox AllOtherNamesTemplate:Chembox IndexlistTemplate:Chembox JmolTemplate:Chembox ECHATemplate:Chembox E numberTemplate:Chembox CompToxTemplate:Chembox Datapage check| Lua error in package.lua at line 80: module 'Module:InfoboxImage/data' not found. | |
| IdentifiersTemplate:Chembox parametercheckScript error: No such module "TemplatePar". | |
|---|---|
| Page Template:Plainlist/styles.css has no content. | |
| ChEBI | Page Template:Plainlist/styles.css has no content. |
| ChEMBL | Page Template:Plainlist/styles.css has no content. |
| ChemSpider | Page Template:Plainlist/styles.css has no content. |
| DrugBank | Page Template:Plainlist/styles.css has no content. |
| EC Number | Page Template:Plainlist/styles.css has no content. |
| Page Template:Plainlist/styles.css has no content. | |
| KEGG | Page Template:Plainlist/styles.css has no content. |
PubChem CID
|
Page Template:Plainlist/styles.css has no content. |
| RTECS number | Page Template:Plainlist/styles.css has no content. |
| UNII | Page Template:Plainlist/styles.css has no content. |
| PropertiesScript error: No such module "TemplatePar". | |
| C19H22N4 | |
| Molar mass | 306.40478 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
| |
Template:Chembox Footer/trackingScript error: No such module "TemplatePar".Template:Short description
Corrin is a heterocyclic compound. Although not known to exist on its own, the molecule is of interest as the parent macrocycle related to the cofactor and chromophore in vitamin B12. Its name reflects that it is the "core" of vitamin B12 (cobalamins). Compounds with a corrin core are known as "corrins".[2]
There are two chiral centres, which in natural compounds like cobalamin have the same stereochemistry.
Coordination chemistry
Script error: No such module "Labelled list hatnote". Upon deprotonation, the corrinoid ring is capable of binding cobalt. In vitamin B12, the resulting complex also features a benzimidazole-derived ligand, and the sixth site on the octahedron serves as the catalytic center.
The corrin ring resembles the porphyrin ring.[3] Both feature four pyrrole-like subunits organized into rings. Corrins have a central 15-membered Template:Chem2 ring whereas porphyrins have an interior 16-membered Template:Chem2 ring. All four nitrogen centers are linked by conjugation structure, with alternating double and single bonds. In contrast to porphyrins, corrins lack one of the carbon groups that link the pyrrole-like units into a fully conjugated structure. With a conjugated system that extends only 3/4 of the way around the ring, and does not include any of the outer edge carbons, corrins have a number of non-conjugated sp3 carbons, making them more flexible than porphyrins and not as flat. A third closely related biological structure, the chlorin ring system found in chlorophyll, is intermediate between porphyrin and corrin, having 20 carbons like the porphyrins and a conjugated structure extending all the way around the central atom, but with only 6 of the 8 edge carbons participating.
Corroles (octadehydrocorrins) are fully aromatic derivatives of corrins.
References
Page Template:Reflist/styles.css has no content.
- ^ https://pubchem.ncbi.nlm.nih.gov/compound/6438343#section=IUPAC-Name&fullscreen=true
- ^ Nelson, D. L.; Cox, M. M. "Lehninger, Principles of Biochemistry" 3rd Ed. Worth Publishing: New York, 2000. Template:ISBN.
- ^ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Utilities' not found.
Further reading
- Lua error in package.lua at line 80: module 'Module:Citation/CS1/Utilities' not found.
Lua error in package.lua at line 80: module 'Module:Navbox/configuration' not found.
