Nitidine

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Nitidine
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Names
Preferred IUPAC name
2,3-Dimethoxy-12-methyl-9H-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
Identifiers
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3D model (JSmol)
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  • InChI=1S/C21H18NO4/c1-22-10-13-7-17(23-2)18(24-3)8-15(13)14-5-4-12-6-19-20(26-11-25-19)9-16(12)21(14)22/h4-10H,11H2,1-3H3/q+1
    Key: KKMPSGJPCCJYRV-UHFFFAOYSA-N
  • InChI=1/C21H18NO4/c1-22-10-13-7-17(23-2)18(24-3)8-15(13)14-5-4-12-6-19-20(26-11-25-19)9-16(12)21(14)22/h4-10H,11H2,1-3H3/q+1
    Key: KKMPSGJPCCJYRV-UHFFFAOYAL
  • C[N+]1=CC2=CC(=C(C=C2C3=C1C4=CC5=C(C=C4C=C3)OCO5)OC)OC
Properties
C21H18NO4+
Molar mass 348.37 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

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Nitidine is a benzophenanthridine alkaloid found in species of the genus Zanthoxylum , notably in Zanthoxylum nitidum. This compound has an anti-malarial activity.[1]

References

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  1. ^ Bouquet, J., et al. (2012). Biological activities of nitidine, a potential anti-malarial lead compound. Malaria Journal 11:67


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