PDGFD

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Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Platelet-derived growth factor D is a protein that in humans is encoded by the PDGFD gene.[1][2][3]

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene.[3]

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content.Hamada T, Ui-Tei K, Imaki J, Miyata Y (Feb 2001). "Molecular cloning of SCDGF-B, a novel growth factor homologous to SCDGF/PDGF-C/fallotein". Biochem Biophys Res Commun. 280 (3): 733–7. doi:10.1006/bbrc.2000.4187. PMID 11162582.
  2. ^ Page Module:Citation/CS1/styles.css has no content.LaRochelle WJ, Jeffers M, Corvalan JR, Jia XC, Feng X, Vanegas S, Vickroy JD, Yang XD, Chen F, Gazit G, Mayotte J, Macaluso J, Rittman B, Wu F, Dhanabal M, Herrmann J, Lichenstein HS (Apr 2002). "Platelet-derived growth factor D: tumorigenicity in mice and dysregulated expression in human cancer". Cancer Res. 62 (9): 2468–73. PMID 11980634.
  3. ^ a b Page Module:Citation/CS1/styles.css has no content."Entrez Gene: PDGFD platelet derived growth factor D".

Further reading

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