PERP

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Template:Short description Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). p53 apoptosis effector related to PMP-22 is a plasma membrane protein that, in humans, is encoded by the PERP gene.[1][2]

PERP is a direct transcriptional target of p53, but its transcription can also be regulated by other transcription factors.[3]

PERP is important for skin development, and loss of PERP is associated with the development and progression of several types of human cancers.[3]

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content.Hildebrandt T, Preiherr J, Tarbe N, Klostermann S, Van Muijen GN, Weidle UH (Dec 2000). "Identification of THW, a putative new tumor suppressor gene". Anticancer Res. 20 (5A): 2801–2809. PMID 11062687.
  2. ^ Page Module:Citation/CS1/styles.css has no content."Entrez Gene: PERP PERP, TP53 apoptosis effector".
  3. ^ a b Page Module:Citation/CS1/styles.css has no content.Roberts O, Paraoan L (Dec 2020). "PERP-ing into diverse mechanisms of cancer pathogenesis: Regulation and role of the p53/p63 effector PERP". Biochim Biophys Acta Rev Cancer. 1874 (1) 188393. doi:10.1016/j.bbcan.2020.188393. PMID 32679166. S2CID 220631324.

Further reading

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