5-MAPDB
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| Other names | 5-(2-(Methylamino)propyl)-2,3-dihydrobenzofuran; 1-(2,3-dihydrobenzofuran-5-yl)-N-methylpropan-2-amine |
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| Formula | C12H17NO |
| Molar mass | 191.274 g·mol−1 |
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5-MAPDB, also known as 5-(2-(methylamino)propyl)-2,3-dihydrobenzofuran, is an entactogen of the dihydrobenzofuran family. It is structurally related to drugs like 5-APDB and 5-MAPB, which have similar effects to MDMA and have been used as recreational drugs. 5-MAPDB has been studied to determine its pharmacological activity, and was found to be a relatively selective serotonin releaser, though with weaker actions as a releaser of other monoamines and 5-HT2 receptor family agonist,[2] similar to older compounds such as 5-APDB.[3]
Interactions
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Society and culture
Legal status
5-MAPDB was banned in the UK in June 2013 as a temporary class drug along with 9 other related compounds, despite having never been sold as a street drug itself. This was due to concerns that it would have similar effects to drugs such as 5-APB that had been widely sold already, and 5-MAPDB might therefore be likely to become used recreationally also, if it were not banned preemptively.[4]
See also
References
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- ^ Page Module:Citation/CS1/styles.css has no content.Anvisa (2023-07-24). "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in português do Brasil). Diário Oficial da União (published 2023-07-25). Archived from the original on 2023-08-27. Retrieved 2023-08-27.
- ^ Page Module:Citation/CS1/styles.css has no content.Rickli A, Kopf S, Hoener MC, Liechti ME (July 2015). "Pharmacological profile of novel psychoactive benzofurans". British Journal of Pharmacology. 172 (13): 3412–25. doi:10.1111/bph.13128. PMC 4500375. PMID 25765500.
- ^ Page Module:Citation/CS1/styles.css has no content.Monte AP, Marona-Lewicka D, Cozzi NV, Nichols DE (November 1993). "Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogues of 3,4-(methylenedioxy)amphetamine". Journal of Medicinal Chemistry. 36 (23): 3700–6. doi:10.1021/jm00075a027. PMID 8246240.
- ^ Page Module:Citation/CS1/styles.css has no content."Temporary class drug order report on 5-6APB and NBOMe compounds". UK Home Office. 4 Jun 2013. Retrieved 2013-07-11.
External links
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