ABCF2
Template:Short description An Error has occurred retrieving Wikidata item for infobox ATP-binding cassette sub-family F member 2 is a protein that in humans is encoded by the ABCF2 gene.[1][2]
Function
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This protein is a member of the GCN20 subfamily. Alternative splicing of this gene results in multiple transcript variants.[2]
ABCF2 acts as a suppressor of the volume-sensitive outwardly rectifying Cl channel (CLCN3).[3]
See also
References
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- ^ Page Module:Citation/CS1/styles.css has no content.Allikmets R, Gerrard B, Hutchinson A, Dean M (October 1996). "Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database". Human Molecular Genetics. 5 (10): 1649–55. doi:10.1093/hmg/5.10.1649. PMID 8894702.
- ^ a b Page Module:Citation/CS1/styles.css has no content."Entrez Gene: ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2".
- ^ Page Module:Citation/CS1/styles.css has no content.Ando-Akatsuka Y, Shimizu T, Numata T, Okada Y (2012). "Involvements of the ABC protein ABCF2 and α-actinin-4 in regulation of cell volume and anion channels in human epithelial cells". Journal of Cellular Physiology. 227 (10): 3498–510. doi:10.1002/jcp.24050. PMID 22252987. S2CID 22139132.
Further reading
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- Page Module:Citation/CS1/styles.css has no content.Klein I, Sarkadi B, Váradi A (December 1999). "An inventory of the human ABC proteins". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1461 (2): 237–62. doi:10.1016/s0005-2736(99)00161-3. PMID 10581359.
- Page Module:Citation/CS1/styles.css has no content.Dean M, Rzhetsky A, Allikmets R (July 2001). "The human ATP-binding cassette (ABC) transporter superfamily". Genome Research. 11 (7): 1156–66. doi:10.1101/gr.184901. PMID 11435397. S2CID 9528197.
- Page Module:Citation/CS1/styles.css has no content.Hogue DL, Liu L, Ling V (January 1999). "Identification and characterization of a mammalian mitochondrial ATP-binding cassette membrane protein". Journal of Molecular Biology. 285 (1): 379–89. doi:10.1006/jmbi.1998.2259. PMID 9878413.
- Page Module:Citation/CS1/styles.css has no content.Zhang F, Hogue DL, Liu L, Fisher CL, Hui D, Childs S, Ling V (July 2000). "M-ABC2, a new human mitochondrial ATP-binding cassette membrane protein". FEBS Letters. 478 (1–2): 89–94. doi:10.1016/S0014-5793(00)01823-8. PMID 10922475. S2CID 41556343.
- Page Module:Citation/CS1/styles.css has no content.Ye Z, Connor JR (August 2000). "cDNA cloning by amplification of circularized first strand cDNAs reveals non-IRE-regulated iron-responsive mRNAs". Biochemical and Biophysical Research Communications. 275 (1): 223–7. doi:10.1006/bbrc.2000.3282. PMID 10944468.
- Page Module:Citation/CS1/styles.css has no content.Stanchi F, Bertocco E, Toppo S, Dioguardi R, Simionati B, Cannata N, Zimbello R, Lanfranchi G, Valle G (January 2001). "Characterization of 16 novel human genes showing high similarity to yeast sequences". Yeast. 18 (1): 69–80. doi:10.1002/1097-0061(200101)18:1<69::AID-YEA647>3.0.CO;2-H. PMID 11124703. S2CID 21397515.
- Page Module:Citation/CS1/styles.css has no content.Tsuda H, Ito YM, Ohashi Y, Wong KK, Hashiguchi Y, Welch WR, Berkowitz RS, Birrer MJ, Mok SC (October 2005). "Identification of overexpression and amplification of ABCF2 in clear cell ovarian adenocarcinomas by cDNA microarray analyses". Clinical Cancer Research. 11 (19 Pt 1): 6880–8. doi:10.1158/1078-0432.CCR-05-0751. PMID 16203778. S2CID 27248404.
- Page Module:Citation/CS1/styles.css has no content.Nishimura S, Tsuda H, Ito K, Jobo T, Yaegashi N, Inoue T, Sudo T, Berkowitz RS, Mok SC (January 2007). "Differential expression of ABCF2 protein among different histologic types of epithelial ovarian cancer and in clear cell adenocarcinomas of different organs". Human Pathology. 38 (1): 134–9. doi:10.1016/j.humpath.2006.06.026. PMID 16996567.
External links
- ABCF2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- ABCF2 human gene location in the UCSC Genome Browser.
- ABCF2 human gene details in the UCSC Genome Browser.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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