AP2B1
From Wikipedia, the free encyclopedia
Template:Short description Template:Cs1 config An Error has occurred retrieving Wikidata item for infobox AP-2 complex subunit beta is a protein that in humans is encoded by the AP2B1 gene.[1][2][3]
Function
The protein encoded by this gene is one of two large chain components of the AP2 adaptor complex, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene.[3]
Interactions
AP2B1 has been shown to interact with:
Page Template:Div col/styles.css has no content.
References
Page Template:Reflist/styles.css has no content.
- ^ Page Module:Citation/CS1/styles.css has no content.Gallusser A, Kirchhausen T (Dec 1993). "The beta 1 and beta 2 subunits of the AP complexes are the clathrin coat assembly components". The EMBO Journal. 12 (13): 5237–44. doi:10.1002/j.1460-2075.1993.tb06219.x. PMC 413789. PMID 8262066.
- ^ Page Module:Citation/CS1/styles.css has no content.Druck T, Gu Y, Prabhala G, Cannizzaro LA, Park SH, Huebner K, Keen JH (Nov 1995). "Chromosome localization of human genes for clathrin adaptor polypeptides AP2 beta and AP50 and the clathrin-binding protein, VCP". Genomics. 30 (1): 94–7. doi:10.1006/geno.1995.0016. PMID 8595912.
- ^ a b Page Module:Citation/CS1/styles.css has no content."Entrez Gene: AP2B1 adaptor-related protein complex 2, beta 1 subunit".
- ^ a b Page Module:Citation/CS1/styles.css has no content.Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
- ^ Page Module:Citation/CS1/styles.css has no content.Laporte SA, Oakley RH, Zhang J, Holt JA, Ferguson SS, Caron MG, Barak LS (Mar 1999). "The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis". Proceedings of the National Academy of Sciences of the United States of America. 96 (7): 3712–7. Bibcode:1999PNAS...96.3712L. doi:10.1073/pnas.96.7.3712. PMC 22359. PMID 10097102.
- ^ Page Module:Citation/CS1/styles.css has no content.Kim YM, Benovic JL (Aug 2002). "Differential roles of arrestin-2 interaction with clathrin and adaptor protein 2 in G protein-coupled receptor trafficking". The Journal of Biological Chemistry. 277 (34): 30760–8. doi:10.1074/jbc.M204528200. PMID 12070169.
- ^ Page Module:Citation/CS1/styles.css has no content.Cayrol C, Cougoule C, Wright M (Nov 2002). "The beta2-adaptin clathrin adaptor interacts with the mitotic checkpoint kinase BubR1". Biochemical and Biophysical Research Communications. 298 (5): 720–30. doi:10.1016/s0006-291x(02)02522-6. PMID 12419313.
- ^ Page Module:Citation/CS1/styles.css has no content.He G, Gupta S, Yi M, Michaely P, Hobbs HH, Cohen JC (Nov 2002). "ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2". The Journal of Biological Chemistry. 277 (46): 44044–9. doi:10.1074/jbc.M208539200. PMID 12221107.
- ^ Page Module:Citation/CS1/styles.css has no content.Yao D, Ehrlich M, Henis YI, Leof EB (Nov 2002). "Transforming growth factor-beta receptors interact with AP2 by direct binding to beta2 subunit". Molecular Biology of the Cell. 13 (11): 4001–12. doi:10.1091/mbc.02-07-0104. PMC 133610. PMID 12429842.
Further reading
Page Template:Refbegin/styles.css has no content.
- Page Module:Citation/CS1/styles.css has no content.Kirchhausen T (2000). "Clathrin". Annual Review of Biochemistry. 69: 699–727. doi:10.1146/annurev.biochem.69.1.699. PMID 10966473.
- Page Module:Citation/CS1/styles.css has no content.Geyer M, Fackler OT, Peterlin BM (Jul 2001). "Structure--function relationships in HIV-1 Nef". EMBO Reports. 2 (7): 580–5. doi:10.1093/embo-reports/kve141. PMC 1083955. PMID 11463741.
- Page Module:Citation/CS1/styles.css has no content.Ponnambalam S, Robinson MS, Jackson AP, Peiperl L, Parham P (Mar 1990). "Conservation and diversity in families of coated vesicle adaptins". The Journal of Biological Chemistry. 265 (9): 4814–20. doi:10.1016/S0021-9258(19)34045-1. PMID 1969413.
- Page Module:Citation/CS1/styles.css has no content.Greenberg ME, Bronson S, Lock M, Neumann M, Pavlakis GN, Skowronski J (Dec 1997). "Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation". The EMBO Journal. 16 (23): 6964–76. doi:10.1093/emboj/16.23.6964. PMC 1170300. PMID 9384576.
- Page Module:Citation/CS1/styles.css has no content.Lim DS, Kirsch DG, Canman CE, Ahn JH, Ziv Y, Newman LS, Darnell RB, Shiloh Y, Kastan MB (Aug 1998). "ATM binds to beta-adaptin in cytoplasmic vesicles". Proceedings of the National Academy of Sciences of the United States of America. 95 (17): 10146–51. Bibcode:1998PNAS...9510146L. doi:10.1073/pnas.95.17.10146. PMC 21476. PMID 9707615.
- Page Module:Citation/CS1/styles.css has no content.Greenberg M, DeTulleo L, Rapoport I, Skowronski J, Kirchhausen T (Nov 1998). "A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4". Current Biology. 8 (22): 1239–42. Bibcode:1998CBio....8.1239G. doi:10.1016/S0960-9822(07)00518-0. PMID 9811611. S2CID 14272751.
- Page Module:Citation/CS1/styles.css has no content.Berlioz-Torrent C, Shacklett BL, Erdtmann L, Delamarre L, Bouchaert I, Sonigo P, Dokhelar MC, Benarous R (Feb 1999). "Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins". Journal of Virology. 73 (2): 1350–61. doi:10.1128/JVI.73.2.1350-1361.1999. PMC 103959. PMID 9882340.
- Page Module:Citation/CS1/styles.css has no content.Owen DJ, Vallis Y, Pearse BM, McMahon HT, Evans PR (Aug 2000). "The structure and function of the beta 2-adaptin appendage domain". The EMBO Journal. 19 (16): 4216–27. doi:10.1093/emboj/19.16.4216. PMC 302036. PMID 10944104.
- Page Module:Citation/CS1/styles.css has no content.Fan GH, Yang W, Wang XJ, Qian Q, Richmond A (Jan 2001). "Identification of a motif in the carboxyl terminus of CXCR2 that is involved in adaptin 2 binding and receptor internalization". Biochemistry. 40 (3): 791–800. doi:10.1021/bi001661b. PMC 2664867. PMID 11170396.
- Page Module:Citation/CS1/styles.css has no content.Swigut T, Shohdy N, Skowronski J (Apr 2001). "Mechanism for down-regulation of CD28 by Nef". The EMBO Journal. 20 (7): 1593–604. doi:10.1093/emboj/20.7.1593. PMC 145469. PMID 11285224.
- Page Module:Citation/CS1/styles.css has no content.Laporte SA, Miller WE, Kim KM, Caron MG (Mar 2002). "beta-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: identification of a beta-arrestin binging site in beta 2-adaptin". The Journal of Biological Chemistry. 277 (11): 9247–54. doi:10.1074/jbc.M108490200. PMID 11777907.
- Page Module:Citation/CS1/styles.css has no content.Collins BM, McCoy AJ, Kent HM, Evans PR, Owen DJ (May 2002). "Molecular architecture and functional model of the endocytic AP2 complex". Cell. 109 (4): 523–35. doi:10.1016/S0092-8674(02)00735-3. PMID 12086608. S2CID 483953.
- Page Module:Citation/CS1/styles.css has no content.He G, Gupta S, Yi M, Michaely P, Hobbs HH, Cohen JC (Nov 2002). "ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2". The Journal of Biological Chemistry. 277 (46): 44044–9. doi:10.1074/jbc.M208539200. PMID 12221107.
- Page Module:Citation/CS1/styles.css has no content.Cayrol C, Cougoule C, Wright M (Nov 2002). "The beta2-adaptin clathrin adaptor interacts with the mitotic checkpoint kinase BubR1". Biochemical and Biophysical Research Communications. 298 (5): 720–30. doi:10.1016/S0006-291X(02)02522-6. PMID 12419313.
- Page Module:Citation/CS1/styles.css has no content.Yao D, Ehrlich M, Henis YI, Leof EB (Nov 2002). "Transforming growth factor-beta receptors interact with AP2 by direct binding to beta2 subunit". Molecular Biology of the Cell. 13 (11): 4001–12. doi:10.1091/mbc.02-07-0104. PMC 133610. PMID 12429842.
- Page Module:Citation/CS1/styles.css has no content.Kalthoff C, Groos S, Kohl R, Mahrhold S, Ungewickell EJ (Nov 2002). "Clint: a novel clathrin-binding ENTH-domain protein at the Golgi". Molecular Biology of the Cell. 13 (11): 4060–73. doi:10.1091/mbc.E02-03-0171. PMC 133614. PMID 12429846.
External links
Lua error in package.lua at line 80: module 'Module:Navbox/configuration' not found.
