ATG9A

From Wikipedia, the free encyclopedia

Template:Short description An Error has occurred retrieving Wikidata item for infobox Autophagy-related protein 9A is a protein that in humans is encoded by the ATG9A gene.[1]

Functional studies indicate that ATG9A plays a role in autophagy.[2][3] and other non-autophagy membrane remodeling processes such as plasma membrane repair.[4] Enzymatically, it is a lipid scramblase.[2][3] ATG9A interacts with IQGAP1 and the ESCRT machinery in membrane remodeling.[4]

References

Page Template:Reflist/styles.css has no content.

  1. ^ Page Module:Citation/CS1/styles.css has no content."Entrez Gene: ATG9A ATG9 autophagy related 9 homolog A (S. cerevisiae)".
  2. ^ a b Page Module:Citation/CS1/styles.css has no content.Maeda S, Yamamoto H, Kinch LN, Garza CM, Takahashi S, Otomo C, et al. (December 2020). "Structure, lipid scrambling activity and role in autophagosome formation of ATG9A". Nature Structural & Molecular Biology. 27 (12): 1194–1201. doi:10.1038/s41594-020-00520-2. PMC 7718406. PMID 33106659.
  3. ^ a b Page Module:Citation/CS1/styles.css has no content.Matoba K, Kotani T, Tsutsumi A, Tsuji T, Mori T, Noshiro D, et al. (December 2020). "Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion". Nature Structural & Molecular Biology. 27 (12): 1185–1193. doi:10.1038/s41594-020-00518-w. PMID 33106658. S2CID 225081989.
  4. ^ a b Page Module:Citation/CS1/styles.css has no content.Claude-Taupin A, Jia J, Bhujabal Z, Garfa-Traoré M, Kumar S, da Silva GP, et al. (July 2021). "ATG9A protects the plasma membrane from programmed and incidental permeabilization". Nature Cell Biology. 23 (8): 846–858. doi:10.1038/s41556-021-00706-w. ISSN 1465-7392. PMC 8276549. PMID 34257406.

Further reading

Page Template:Refbegin/styles.css has no content.

Template:Asbox