Alphenal

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Alphenal
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Clinical data
Trade namesAlphenal, Efrodal, Prophenal, Sanudorm
Other names5-Phenyl-5-allylbarbituric acid
Routes of
administration		By mouth
Drug classBarbiturate
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  • none
Legal status
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Identifiers
  • 5-phenyl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
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Chemical and physical data
FormulaC13H12N2O3
Molar mass244.250 g·mol−1
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Data page
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Alphenal, also known as 5-allyl-5-phenylbarbituric acid, is a barbiturate derivative developed in the 1920s.[1] It has primarily anticonvulsant properties and was used occasionally for the treatment of epilepsy or convulsions, although not as commonly as better known barbiturates such as phenobarbital.[2][3][4][5]

LD50: Mouse (Oral): 280 mg/kg

References

  1. ^ Page Template:Citation/styles.css has no content.DE 526854, "Verfahren zur Darstellung von C,C-disubstituierten Barbitursaeuren", issued Script error: No such module "auto date formatter"., assigned to Hoffmann La Roche 
  2. ^ Page Module:Citation/CS1/styles.css has no content.Carissimi M (1962). "Nuovi Barbiturici Alogenati Farmaco". Ediozione Scientifica. 17 (6): 390–413.
  3. ^ Page Module:Citation/CS1/styles.css has no content.Martin JR, Godel T, Hunkeler W, Jenck F, Moreau JL, Sleight AJ, Widmer U (December 2000). "Psychopharmacological Agents". Kirk-Othmer Encyclopedia of Chemical Technology. doi:10.1002/0471238961.1619250313011820.a01. ISBN 0471238961.
  4. ^ Page Module:Citation/CS1/styles.css has no content.Brandenberger H, Maes RA (1997). Analytical Toxicology: For Clinical, Forensic, and Pharmaceutical Chemists. Walter de Gruyter. p. 348. ISBN 978-3-11-010731-9. Retrieved 19 May 2012.
  5. ^ Page Module:Citation/CS1/styles.css has no content.García PC, Cruz SV, Mirón CE (28 January 2005). Fundamentos de síntesis de fármacos. Edicions Universitat Barcelona. p. 161. ISBN 978-84-475-2876-9. Retrieved 19 May 2012.


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