Anhalamine
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| Preferred IUPAC name
6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-8-ol | |
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3D model (JSmol)
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| Properties | |
| C11H15NO3 | |
| Molar mass | 209.245 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Template:Chembox Footer/trackingTemplate:Short description
Anhalamine is a naturally occurring tetrahydroisoquinoline alkaloid which can be isolated from Lophophora williamsii.[1] It is structurally related to mescaline.[2] It has been found to act as a potent inverse agonist of the serotonin 5-HT7 receptor.[3]
See also
References
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- ^ Page Module:Citation/CS1/styles.css has no content.Lundström, J; Agurell, S (August 1968). "Biosynthesis of mescaline and anhalamine in peyote. IIa". Tetrahedron Letters. 9 (42): 4437–40. doi:10.1016/s0040-4039(01)99153-1. PMID 5672059.
- ^ Page Module:Citation/CS1/styles.css has no content.Ghansah, E.; Kopsombut, P.; Maleque, M.A.; Brossi, A. (February 1993). "Effects of mescaline and some of its analogs on cholinergic neuromuscular transmission". Neuropharmacology. 32 (2): 169–174. doi:10.1016/0028-3908(93)90097-M. PMID 8383816. S2CID 42388554.
- ^ Page Module:Citation/CS1/styles.css has no content.Chan CB, Pottie E, Simon IA, Rossebø AG, Herth MM, Harpsøe K, Kristensen JL, Stove CP, Poulie CB (February 2025). "Synthesis, Pharmacological Characterization, and Binding Mode Analysis of 8-Hydroxy-Tetrahydroisoquinolines as 5-HT7 Receptor Inverse Agonists". ACS Chem Neurosci. 16 (3): 439–451. doi:10.1021/acschemneuro.4c00667. hdl:1854/LU-01JQ6WFR8R7G85440FRY2248HG. PMID 39836645.
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