Azapropazone

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Azapropazone
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Clinical data
Trade namesRheumox
AHFS/Drugs.comInternational Drug Names
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Legal status
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Pharmacokinetic data
Elimination half-life20 hours
Identifiers
  • (RS)-5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo[1,2-a][1,2,4]benzotriazine-1,3(2H)-dione
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Chemical and physical data
FormulaC16H20N4O2
Molar mass300.362 g·mol−1
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ChiralityRacemic mixture
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Azapropazone is a nonsteroidal anti-inflammatory drug (NSAID). It is manufactured by Goldshield under the tradename Rheumox.[1]

It was available in the UK as a prescription-only drug, with restrictions due to certain contra-indications and side-effects.[2] Azopropazone has now been discontinued in the British National Formulary.

Azapropazone has a half-life of approximately 20 hours in humans and is not extensively metabolized.[3]

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content."Rheumox Capsules". South Africa Electronic Package Inserts. Archived from the original on 2008-05-15. Retrieved 2008-08-18.
  2. ^ Page Module:Citation/CS1/styles.css has no content."Azapropazone". Patient UK. Archived from the original on 12 April 2009.
  3. ^ Page Module:Citation/CS1/styles.css has no content.Jones CJ (1976). "The pharmacology and pharmacokinetics of azapropazone - a review". Current Medical Research and Opinion. 4 (1): 3–16. doi:10.1185/03007997609109277. PMID 770078.

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