Beractant

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Beractant
Clinical data
Trade namesSurvanta, others
AHFS/Drugs.comMonograph
Routes of
administration		Endotracheal
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  • None
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Identifiers
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Beractant, also known by the trade name of Survanta, is a modified bovine pulmonary surfactant containing bovine lung extract (phospholipids, neutral lipids, fatty acids, and bovine surfactant proteins), to which synthetic DPPC, tripalmitin and palmitic acid are added. The composition provides 25 mg/mL phospholipids, 0.5 to 1.75 mg/mL triglycerides, 1.4 to 3.5 mg/mL free fatty acids, and <1.0 mg/mL total surfactant proteins.[1] As an intratracheal suspension, it can be used for the prevention and treatment of neonatal respiratory distress syndrome.[2] Survanta is manufactured by Abbvie.

Beractant is on the World Health Organization's List of Essential Medicines.[3]

Generic form

Beraksurf is generic form of Survanta (Beractant) which is manufacturing by Tekzima.

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content.Moya FR, Gadzinowski J, Bancalari E, Salinas V, Kopelman B, Bancalari A, et al. (April 2005). "A multicenter, randomized, masked, comparison trial of lucinactant, colfosceril palmitate, and beractant for the prevention of respiratory distress syndrome among very preterm infants". Pediatrics. 115 (4): 1018–29. doi:10.1542/peds.2004-2183. PMID 15805380. S2CID 40458323.{{cite journal}}: CS1 maint: overridden setting (link)
  2. ^ Page Module:Citation/CS1/styles.css has no content.Lotze A, Mitchell BR, Bulas DI, Zola EM, Shalwitz RA, Gunkel JH (January 1998). "Multicenter study of surfactant (beractant) use in the treatment of term infants with severe respiratory failure. Survanta in Term Infants Study Group". The Journal of Pediatrics. 132 (1): 40–7. doi:10.1016/S0022-3476(98)70482-2. PMID 9469998.
  3. ^ Page Module:Citation/CS1/styles.css has no content.World Health Organization (2025). The selection and use of essential medicines, 2025: WHO Model List of Essential Medicines, 24th list. Geneva: World Health Organization. hdl:10665/382243.

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