Ceforanide

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Ceforanide
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Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Intramuscular
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Pharmacokinetic data
Protein binding80.6%
MetabolismNil
Elimination half-life2.6 to 2.98 hours
ExcretionRenal
Identifiers
  • (6R,7R)-7-{[2-[2-(aminomethyl)phenyl]acetyl]amino}-3-
    {[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl}-8-oxo-
    5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
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Chemical and physical data
FormulaC20H21N7O6S2
Molar mass519.55 g·mol−1
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  • O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)Cc3ccccc3CN)CSc4nnnn4CC(=O)O)C(=O)O
  • InChI=1S/C20H21N7O6S2/c21-6-11-4-2-1-3-10(11)5-13(28)22-15-17(31)27-16(19(32)33)12(8-34-18(15)27)9-35-20-23-24-25-26(20)7-14(29)30/h1-4,15,18H,5-9,21H2,(H,22,28)(H,29,30)(H,32,33)/t15-,18-/m1/s1 checkY
  • Key:SLAYUXIURFNXPG-CRAIPNDOSA-N checkY
Data page
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Ceforanide is a second-generation cephalosporin antibiotic.[1][2][3]

See also

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content.Crowle A, Sbarbaro J, May M (1988). "Effects of isoniazid and of ceforanide against virulent tubercle bacilli in cultured human macrophages". Tubercle. 69 (1): 15–25. doi:10.1016/0041-3879(88)90036-0. PMID 3140456.
  2. ^ Page Module:Citation/CS1/styles.css has no content.Campoli-Richards D, Lackner T, Monk J (1987). "Ceforanide. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy". Drugs. 34 (4): 411–37. doi:10.2165/00003495-198734040-00001. PMID 3315624. S2CID 242440792.
  3. ^ Page Module:Citation/CS1/styles.css has no content.Cone L, Barton S, Woodard D (1987). "Treatment of scleroma with ceforanide". Arch Otolaryngol Head Neck Surg. 113 (4): 374–6. doi:10.1001/archotol.1987.01860040036012. PMID 3814386.

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