Chlorphenoxamine

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Chlorphenoxamine
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Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Oral, topical
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Pharmacokinetic data
BioavailabilityWell absorbed
MetabolismLikely liver
Excretionkidney
Identifiers
  • {2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl}dimethylamine
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Chemical and physical data
FormulaC18H22ClNO
Molar mass303.83 g·mol−1
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  • Clc1ccc(cc1)C(OCCN(C)C)(c2ccccc2)C
  • InChI=1S/C18H22ClNO/c1-18(21-14-13-20(2)3,15-7-5-4-6-8-15)16-9-11-17(19)12-10-16/h4-12H,13-14H2,1-3H3 checkY
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Chlorphenoxamine (Phenoxene) is an antihistamine and anticholinergic used as an antipruritic[1] and antiparkinsonian[2] agent. It is an analog of diphenhydramine.[3]

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content.Bazex A, Dupre A, Christol B (1963). "[Trial treatment of urticaria with chlorphenoxamine]". Clinique. 58: 447–50. PMID 13967113.
  2. ^ Page Module:Citation/CS1/styles.css has no content.Uldall PR, Walton JN, Newell DJ (June 1961). "Chlorphenoxamine hydrochloride in parkinsonism. A controlled trial". British Medical Journal. 1 (5240): 1649–52. doi:10.1136/bmj.1.5240.1649. PMC 1954253. PMID 13779077.
  3. ^ Page Module:Citation/CS1/styles.css has no content.Arnold H, Brock N, Kuhas E, Lorenz D (January 1954). "Beitrag Zur Wirkung Von Antihistamin-Substanzen. 1. Chemische Konstitution Und Pharmakologische Wirkung in Der Gruppe Der Basischen Benzhydrylaether" [Contribution to the Effect Of Antihistamine Substances. 1. Chemical constitution and pharmacological activity in the group of basic benzhydrylethers]. Arzneimittel-Forschung [Drug Research] (in German). 4 (3): 189–94. PMID 13159698.{{cite journal}}: CS1 maint: unrecognized language (link)

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