Citiolone

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Citiolone
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Clinical data
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Identifiers
  • (RS)-N-(2-Oxothiolan-3-yl)acetamide
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Chemical and physical data
FormulaC6H9NO2S
Molar mass159.20 g·mol−1
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  • InChI=1S/C6H9NO2S/c1-4(8)7-5-2-3-10-6(5)9/h5H,2-3H2,1H3,(H,7,8) checkY
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Citiolone is a drug used in liver therapy.

It is a derivative of the amino acid homocysteine.[1] Citilone has also been studied with regard to hypothermia due to it being a hydroxyl free radical scavenger. The drug has been shown to protect hamster cells subjected to temperature conditions of 8-25 °C.[2]

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content.de Barrio M, Tornero P, Prieto A, Sainza T, Zubeldia JM, Herrero T (1997). "Recurrent fixed drug eruption caused by citiolone". Journal of Investigational Allergology & Clinical Immunology. 7 (3): 193–194. PMID 9252880.
  2. ^ Page Module:Citation/CS1/styles.css has no content.Kruuv J, Glofcheski DJ (June 1993). "Further evidence for two modes of hypothermia damage". Cryobiology. 30 (3): 313–321. doi:10.1006/cryo.1993.1030. PMID 8370318.

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