Exudate

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Exudate from a wound on a human finger
Tree resin is a type of plant exudate.

An exudate is a fluid released by an organism through pores or a wound, a process known as exuding or exudation.[1] Exudate is derived from exude 'to ooze'[2] from Latin Script error: No such module "Lang". 'to (ooze out) sweat' (Script error: No such module "Lang". 'out' and Script error: No such module "Lang". 'to sweat').[3]

Medicine

An exudate is any fluid that filters from the circulatory system into lesions or areas of inflammation. It can be a pus-like or clear fluid. When an injury occurs, leaving skin exposed, it leaks out of the blood vessels and into nearby tissues. The fluid is composed of serum, fibrin, and leukocytes. Exudate may ooze from cuts or from areas of infection or inflammation.[4] Although blood itself is not an exudate,[5] some types of exudates contain blood cells.[6]

Types

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Transudate Exudate
Main causes ↑ hydrostatic
pressure,
↓ colloid
osmotic pressure 		Inflammation, increased
vascular permeability
Appearance Clear[7] Cloudy[7]
Specific gravity < 1.012 > 1.020
Protein content < 2.5 g/dL > 2.9 g/dL[8]
fluid [protein]
serum [protein]		 < 0.5 > 0.5[9]
SAAG =
serum [albumin] − fluid [albumin]		 > 1.2 g/dL < 1.2 g/dL[10]
fluid LDH
upper limit for serum		 < 0.6 or < Page Template:Fraction/styles.css has no content.2⁄3 > 0.6[8] or > Page Template:Fraction/styles.css has no content.2⁄3[9]
Cholesterol content < 45 mg/dL > 45 mg/dL
Radiodensity on CT scan 2 to 15 HU[11] 4 to 33 HU[11]
  • Purulent or suppurative exudate consists of plasma with both active and dead neutrophils, fibrinogen, and necrotic parenchymal cells. This kind of exudate is consistent with more severe infections, and is commonly referred to as pus.
  • Fibrinous exudate is composed mainly of fibrinogen and fibrin. It is characteristic of rheumatic carditis, but is seen in all severe injuries such as strep throat and bacterial pneumonia. Fibrinous inflammation is often difficult to resolve due to blood vessels growing into the exudate and filling space that was occupied by fibrin. Often, large amounts of antibiotics are necessary for resolution.
  • Catarrhal exudate is seen in the nose and throat and is characterized by a high content of mucus.
  • Serous exudate (sometimes classified as serous transudate) is usually seen in mild inflammation, with relatively low protein.[12] Its consistency resembles that of serum, and can usually be seen in certain disease states like tuberculosis. (See below for difference between transudate and exudate)
  • Malignant (or cancerous) pleural effusion is effusion where cancer cells are present.[13] It is usually classified as exudate.

Types of exudates: serous, serosanguineous, sanguineous, hemorrhaging and purulent drainage.

  • Serous: Clear straw colored liquid that drains from the wound. This is a normal part of the healing process.
  • Serosanguineous: Small amount of blood is present in the drainage; it is pink in color due to the presence of red blood cells mixed with serous drainage. This is a normal part of the healing process.
  • Sanguineous: This type of drainage contains red blood due to trauma of blood vessels, this may occur while cleaning the wound. Sanguineous drainage is abnormal.
  • Hemorrhaging: This type of drainage contains frank blood from a leaking blood vessel. This will require emergency treatment to control the bleed. This type of drainage is abnormal.
  • Purulent drainage: This type of drainage is malodorous and can be yellow, gray, or greenish in color. This is an indication of an infection.

Exudates vs. transudates

There is an important distinction between transudates and exudates. Transudates are caused by disturbances of hydrostatic or colloid osmotic pressure, not by inflammation. They have a low protein content in comparison to exudates. Medical distinction between transudates and exudates is through the measurement of the specific gravity of extracted fluid. Specific gravity is used to measure the protein content of the fluid. The higher the specific gravity, the greater the likelihood of capillary permeability changes in relation to body cavities. For example, the specific gravity of the transudate is usually less than 1.012 and a protein content of less than 2 g/100 mL (2 g%). Rivalta test may be used to differentiate an exudate from a transudate. It is not clear if there is a distinction in the difference of transudates and exudates in plants.

Plant exudates

Plant exudates include saps, gums, latex, resin, and kino. Sometimes nectar is considered an exudate.[14] Plant seeds exudate a variety of molecules into the spermosphere,[15] and roots exudate into the rhizosphere; these exudates include acids, sugars, polysaccharides and ectoenzymes, and collectively account for 40% of root carbon.[16] Exudation of these compounds has various benefits to the plant and to the microorganisms of the rhizosphere.[17][18]

See also

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content."exudate". The Free Dictionary - Medical. Retrieved 5 August 2014.
  2. ^ Page Module:Citation/CS1/styles.css has no content.""Exude" Merriam-Webster Online Dictionary". Merriam Webster. 2008. Retrieved 2008-07-04.
  3. ^ Page Module:Citation/CS1/styles.css has no content.Robert K. Barnhart, ed. (1988). Chambers Dictionary of Etymology. New York: Chambers Harrap Publishers. p. 363. ISBN 0-550-14230-4.
  4. ^ Page Module:Citation/CS1/styles.css has no content."Exudate". MedlinePlus.
  5. ^ Page Module:Citation/CS1/styles.css has no content."Medical Definition of Exudate". RxList. Retrieved 28 June 2025.
  6. ^ Page Module:Citation/CS1/styles.css has no content.Carole Jakucs; Zelda Meeker (26 January 2023). "Exudate: What the Types and Quantities Tell You". WCEI. Wound Care Education Institute. Retrieved 28 June 2025.
  7. ^ a b The University of Utah • Spencer S. Eccles Health Sciences Library > WebPath images > Page Module:Citation/CS1/styles.css has no content."Inflammation".
  8. ^ a b Page Module:Citation/CS1/styles.css has no content.Heffner J, Brown L, Barbieri C (1997). "Diagnostic value of tests that discriminate between exudative and transudative pleural effusions. Primary Study Investigators". Chest. 111 (4): 970–80. doi:10.1378/chest.111.4.970. PMID 9106577.
  9. ^ a b Page Module:Citation/CS1/styles.css has no content.Light R, Macgregor M, Luchsinger P, Ball W (1972). "Pleural effusions: the diagnostic separation of transudates and exudates". Ann Intern Med. 77 (4): 507–13. doi:10.7326/0003-4819-77-4-507. PMID 4642731.
  10. ^ Page Module:Citation/CS1/styles.css has no content.Roth BJ, O'Meara TF, Gragun WH (1990). "The serum-effusion albumin gradient in the evaluation of pleural effusions". Chest. 98 (3): 546–9. doi:10.1378/chest.98.3.546. PMID 2152757.
  11. ^ a b Page Module:Citation/CS1/styles.css has no content.Cullu, Nesat; Kalemci, Serdar; Karakas, Omer; Eser, Irfan; Yalcin, Funda; Boyaci, Fatma Nurefsan; Karakas, Ekrem (2013). "Efficacy of CT in diagnosis of transudates and exudates in patients with pleural effusion". Diagnostic and Interventional Radiology. 20: 116–20. doi:10.5152/dir.2013.13066. ISSN 1305-3825. PMC 4463296. PMID 24100060.
  12. ^ Robbins Basic Pathology 7th ed
  13. ^ About.com > Malignant Pleural Effusion Script error: No such module "webarchive". By Lynne Eldridge MD. Updated March 27, 2010
  14. ^ Page Module:Citation/CS1/styles.css has no content.Power, Michael L. (2010). Anne M. Burrows; Leanne T. Nash (eds.). The Evolution of Exudativory in Primates / Nutritional and Digestive Challenges to Being a Gum-feeding Primate. Springer. p. 28. ISBN 9781441966612. Retrieved 2 October 2012.
  15. ^ Page Module:Citation/CS1/styles.css has no content.Schiltz, S; Gaillard, I; Pawlicki-Jullian, N; Thiombiano, B; Mesnard, F; Gontier, E (December 2015). "A review: what is the spermosphere and how can it be studied?". Journal of Applied Microbiology. 119 (6): 1467–81. doi:10.1111/jam.12946. PMID 26332271. S2CID 42515027.
  16. ^ Page Module:Citation/CS1/styles.css has no content.Marschner, Horst (1995). Mineral Nutrition of Higher Plants. ISBN 0124735436.
  17. ^ Page Module:Citation/CS1/styles.css has no content.Walker, T. S.; Bais, H. P.; Grotewold, E.; Vivanco, J. M. (2003). "Root Exudation and Rhizosphere Biology". Plant Physiology. 132 (1): 44–51. doi:10.1104/pp.102.019661. PMC 1540314. PMID 12746510.
  18. ^ Page Module:Citation/CS1/styles.css has no content.Martins, S. J.; Medeiros, F. H. V.; Lakshmanan, V.; Bais, H. P. (2018). "Impact of Seed Exudates on Growth and Biofilm Formation of Bacillus amyloliquefaciens ALB629 in Common Bean". Frontiers in Microbiology. 8 2631. doi:10.3389/fmicb.2017.02631. PMC 5767182. PMID 29375501.
  • Page Template:Sister-inline/styles.css has no content.Script error: No such module "Sister project logo". Media related to Script error: No such module "Commons link". at Wikimedia Commons

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