International Genetically Engineered Machine

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iGEM
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DateTemplate:Pluralize from textNovember, 13 - 16 (2026)
FrequencyAnnually
VenueParis Expo Porte de Versailles, France (2022~)
Hynes Convention Center, Boston, United States (2014-2019)
MIT, Boston, United States (2003-2013)
LocationTemplate:Pluralize from textParis, France (2022~)
Boston, Massachusetts, United States (2003-2019)
With additional events worldwide
Inaugurated2003
Most recent
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iGEMersAnnually: 10 000+ participants, 400+ teams

Since 2003: 100 000+ participants, 5000+ teams
Organised byiGEM Foundation
Websiteigem.org

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The iGEM (International Genetically Engineered Machine) competition is a worldwide synthetic biology competition that was initially aimed at undergraduate and 'overgraduate' university students, but has since expanded to include divisions for high school students, entrepreneurs, and community laboratories. iGEM is presented as "the heart of synthetic biology" - educating the next generation of leaders and workforce of the field. Since its inception in 2003, over 100 000 students from over 66 countries have been trained in the responsible, safe and secure use of synthetic biology.

The iGEM Competition is a flagship program of the iGEM Foundation - an independent, non-profit organization dedicated to the advancement of synthetic biology, education and competition, and the development of an open, collaborative, and cooperative community. Aside from the competition, iGEM has established many initiatives and programs to support the future growth of synthetic biology throughout the world: iGEM Community, iGEM Technology, iGEM Responsibility, iGEM Startups, and iGEM Leagues.

Competition details

Student teams are given a kit (so called ‘Distribution Kit’) of standard, interchangeable parts (so called 'BioBricks') at the beginning of the summer from the Registry of Standard Biological Parts comprising various genetic components such as promoters, terminators, reporter elements, and plasmid backbones. Working at their local laboratories over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells.

The teams are free to choose a project, which can build on previous projects or be new to iGEM. Successful projects produce cells that exhibit new and unusual properties by engineering sets of multiple genes together with mechanisms to regulate their expression.

At the end of the summer, the teams add their new BioBricks to the Parts Registry and the scientific community can build upon the expanded set of BioBricks in the next year.

At the annual ‘iGEM Jamboree’ teams from all continents meet in Paris for a scientific expo event and conference where they present their projects to each other and to a scientific jury of ~400 judges. The judges award medals and special prizes to the teams and select a ‘Grand Prize Winner’ team as well as ‘Runner-Up’ teams in each division (High School, Undergraduate and Overgraduate).

Awards & Judging in the iGEM competition

Each participant receives a participating certificate (see fig. below) and has the possibility to earn medals (bronze, silver and gold; see fig. below) with their team depending on different criteria that the team fulfilled in the competitions. For a bronze medal it is for example necessary to submit a new part to the Parts Registry, for a silver medal the team is required to document the functionality of a part and for a gold medal it is finally, among other criteria, necessary to obtain a proof-of-principle for the team's project.

In 2016 as an example, 300 teams participated in the competition from which 37% received a gold medal, 25% a silver medal, 26% a bronze medal and 12% were not awarded a medal.

In each division, the best performance in a certain aspect of the competition is honored with special prizes. The special prizes include: 'Best Project' in the respective categories (app. 10 categories), 'Best Art & Design', 'Best Hardware', 'Best Measurement', 'Best Software', 'Best Human Practices', 'Best Model', 'Best New Part', 'Best Poster', 'Best Presentation', 'Best Wiki' and others depending on the competition year. Together with individual certificates, the teams are given glass trophies for each special prize (see fig. below).

From all teams in a respective division, a number of finalists are selected (1 to 6, depending on year and division) and allowed to present their project again in front of all Jamboree participants. From the presented projects all judges select the winner of this year's iGEM competition, the Grand Prize Winner team, who are then awarded a big metal Lego-brick (see fig. below). The winning team may keep this challenge trophy for a year until it gets awarded to the next 'Grand Prize Winner'. Participants of a 'Grand Prize Winner' team are also given challenge coins of the respective year (see fig. below).

History of the competition

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Growth of the annual iGEM Jamboree[1]
Year No. of participants
2004
31(5 teams)
2005
125(13 teams)
2006
723(32 teams)
2007
777(54 teams)
2008
1,248(88 teams)
2009
1,840(113 teams)
2010
2,327(128 teams)
2011
2,586(165 teams)
2012
3,696(190 teams)
2013
4,027(215 teams)
2014
4,515(245 teams)
2015
5,018(280 teams)
2016
4,432(300 teams)
2017
5,386(310 teams)
2018
5,790(340 teams)
2019
6,375(353 teams)
2020
4,800(249 teams)
2021
7,314(350 teams)
2022
7,757(356 teams)
2023
8,541(390 teams)
2024
9,507(410 teams)

iGEM developed out of student projects conducted during MIT's Independent Activities Periods in 2003 and 2004 led by Tom Knight, Drew Endy and Randy Rettberg.[2][3] Later in 2004, a competition with five teams from various schools was held. In 2005, teams from outside the United States took part for the first time.[4] Since then iGEM has continued to grow, with 130 teams entering in 2010.[5][6] Randy Rettberg, an engineer who has worked for technology companies including Apple, Sun and BBN,[7] is the founder and president of iGEM.

Because of this increasing size, in the years 2011 - 2013 the competition was split into three regions: Europe, the Americas, and Asia (though teams from Africa and Australia also entered via "Europe" and "Asia" respectively).[8] Regional jamborees occurred during October; and some subset of teams attending those events were selected to advance to the World Championship at MIT in November.[9]

In January 2012 the iGEM Foundation was spun out of MIT as an independent non-profit organization located in Cambridge, Massachusetts, USA. The iGEM Foundation supports scientific research and education through operating the iGEM competition. The same year, iGEM expanded into having not only the Collegiate division, but also competitions for entrepreneurs and high school students.

For their tenth anniversary, iGEM added new tracks to the existing ones: Art & Design, Community Labs, Entrepreneurship, Measurement, Microfluidics, Policy & Practice, and Software. Although Entrepreneurship and Software were tracks in previous years, in 2014 they were made more distinct in terms of their judging requirements.[10] Furthermore, in 2014 iGEM did not have regional jamborees, but instead hosted a giant jamboree so every team could participate in one conference in Cambridge unlike in previous years where only the regional finalists were brought to Cambridge.[11]

The iGEM Jamborees for 2020 and 2021 were held online, due to the COVID-19 pandemic.

Starting in 2022, the event was redesigned and rebranded to the iGEM Grand Jamboree, held in the Paris Expo Porte de Versailles.

Broader goals

Beyond just building biological systems, broader goals of iGEM include:

  • To enable the systematic engineering of biology.
  • To promote the open and transparent development of tools for engineering biology.
  • And to help construct a society that can productively and safely[12] apply biological technology.

iGEM's dual aspects of self-organization and imaginative manipulation of genetic material have demonstrated a new way to arouse student interest in modern biology and to develop their independent learning skills.

Competition Results

File:Best iGEM Medal by Country.svg
Best iGEM Medal by Country - All Divisions as of November 2024.Page Template:Legend/styles.css has no content.
  Gold Medal
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  Silver Medal
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  Bronze Medal

High School Division

File:IGEM Grand Prize Winners High School 2019.svg
Grand Prize Winners by Country - High School (as of November 2024).Page Template:Legend/styles.css has no content.
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  5 Titles
Top High School Teams by Year
Grand Prize 2nd 3rd Complete Results
2025 GreatBay-SCIE Template:Flagicon Uprize-I Template:Flagicon iGEM 2025
2024 GEMS-Taiwan Template:Flagicon GreatBay-Scie Template:Flagicon iGEM 2024
2023 Japan-United Template:Flagicon BASIS-China Template:Flagicon iGEM 2023
2022 Lambert_GA Template:Flagicon PuiChing_Macau Template:Flagicon iGEM 2022
2021 LINKS_China Template:Flagicon SZ_SHD Template:Flagicon iGEM 2021
2020 TAS Taipei Template:Flagicon GreatBay SCIE Template:Flagicon iGEM 2020
2019 GreatBay SZ Template:Flagicon iGEM 2019[permanent dead link]
2018 GreatBay China Template:Flagicon[note 1] iGEM 2018[permanent dead link]
2017 TAS Taipei Template:Flagicon iGEM 2017
2016 HSiTAIWAN Template:Flagicon iGEM 2016
2015 TAS Taipei Template:Flagicon iGEM HS 2015
2014 CSIA-SouthKorea Template:Flagicon TP CC-SanDiego Template:Flagicon[note 2] TAS TaipeiTemplate:Flagicon iGEM HS 2014
2013 Lethbridge Canada Template:Flagicon AUC Turkey Template:Flagicon CIDEB-UANL Mexico Template:Flagicon iGEM HS 2013
2012 Heidelberg LSL Template:Flagicon NC School of Sci Math Template:Flagicon CIDEB-UANL Mexico Template:Flagicon iGEM HS 2012
2011 Years prior to 2012 had no separate high school division.

High School Ranking by Country

Country Grand Prize Runners-up Top 2 Total
File:Flag of the Republic of China.svg Taiwan 5 0 5
File:Flag of the People's Republic of China.svg China 4 5 9
File:Flag of the United States.svg United States 1 2 3
File:Flag of Canada (Pantone).svg Canada 1 0 1
File:Flag of Germany.svg Germany 1 0 1
File:Flag of Japan.svg Japan 1 0 1
File:Flag of South Korea.svg South Korea 1 0 1
File:Flag of Macau.svg Macao 0 1 1
File:Flag of Turkey.svg Turkey 0 1 1

Undergraduate Division

File:IGEM Grand Prize Winners Undergrad 2019.svg
Grand Prize Winners by Country/Region - Undergrad (as of November 2024).Page Template:Legend/styles.css has no content.
  1 Title
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  3 Titles
Top Undergraduate Teams by Year
Grand Prize 2nd 3rd Complete Results
2025 McGill Template:Flagicon EPFL Template:Flagicon IZJU-China Template:Flagicon iGEM 2025
2024 Heidelberg Template:Flagicon JU-Krakow Template:Flagicon Sydney-Australia Template:Flagicon iGEM 2024
2023 McGill Template:Flagicon Vilnius-Lithuania Template:Flagicon NUS-Singapore Template:Flagicon iGEM 2023
2022 TU-Eindhoven Template:Flagicon INSA_Lyon1 Template:Flagicon HKUST Template:Flagicon iGEM 2022
2021 Toulouse INSA-UPS Template:Flagicon NUS-Singapore Template:Flagicon Shanghai Tech China Template:Flagicon iGEM 2021
2020 Vilnius-Lithuania Template:Flagicon Toulouse INSA-UPS Template:Flagicon XMU China Template:Flagicon iGEM 2020
2019 NCKU Tainan Template:Flagicon Calgary Template:Flagicon TU Kaiserslautern Template:Flagicon iGEM 2019[permanent dead link]
2018 Valencia Template:Flagicon UC San Diego Template:Flagicon SZU-China Template:Flagicon iGEM 2018[permanent dead link]
2017 Vilnius-Lithuania Template:Flagicon William and Mary Template:Flagicon Heidelberg Template:Flagicon iGEM 2017
2016 Imperial Template:Flagicon Sydney Australia Template:Flagicon SCAU-China Template:Flagicon iGEM 2016
2015 William and Mary Template:Flagicon Czech Republic Template:Flagicon Heidelberg Template:Flagicon iGEM 2015
2014 Heidelberg Template:Flagicon Imperial Template:Flagicon NCTU Formosa Template:Flagicon iGEM 2014
2013 Heidelberg Template:Flagicon TU Munich Template:Flagicon Imperial Template:Flagicon iGEM 2013[note 3]
2012 Groningen Template:Flagicon Ljubljana Template:Flagicon Paris Bettencourt Template:Flagicon[note 4] LMU Munich Template:Flagicon iGEM 2012
2011 Washington Template:Flagicon Imperial Template:Flagicon ZJU Chin a Template:Flagicon MIT Template:Flagicon iGEM 2011 [note 5]
2010 Ljubljana Template:Flagicon Peking Template:Flagicon BCCS Bristol Template:Flagicon Cambridge Template:Flagicon Imperial Template:Flagicon TU Delft Template:Flagicon iGEM 2010 Script error: No such module "webarchive".
2009 Cambridge Template:Flagicon Heidelberg Template:Flagicon Valencia Template:Flagicon Freiburg Template:Flagicon Groningen Template:Flagicon Imperial Template:Flagicon iGEM 2009 Script error: No such module "webarchive".
2008 Ljubljana Template:Flagicon Freiburg Template:Flagicon Caltech Template:Flagicon Harvard Template:Flagicon NYMU Taipei Template:Flagicon UC Berkeley Template:Flagicon iGEM 2008
2007 Peking Template:Flagicon Paris Template:Flagicon Ljubljana Template:Flagicon UC Berkeley Template:Flagicon UCSF Template:Flagicon USTC Template:Flagicon iGEM 2007 [note 6]
2006 Ljubljana Template:Flagicon Imperial Template:Flagicon Princeton Template:Flagicon iGEM 2006
2005 Years prior to 2006 had no specific winners. iGEM 2005
2004 IAP 2004, SBC 2004
2003 IAP 2003

Undergraduate Ranking by Country

Country Grand Prize Runners-up 2nd Runners-Up Top 3 Total
File:Flag of Germany.svg Germany 3 3 3 9
File:Flag of Slovenia.svg Slovenia 3 1 1 5
File:Flag of the United Kingdom (1-2).svg United Kingdom 2 3 2 7
File:Flag of the United States.svg United States 2 2 2 6
File:Flag of Lithuania.svg Lithuania 2 1 0 3
File:Flag of the Netherlands.svg Netherlands 2 0 0 2
File:Flag of France.svg France 1 3 1 5
File:Flag of the People's Republic of China.svg China 1 1 6 8
File:Flag of Canada (Pantone).svg Canada 2 1 0 3
File:Flag of Chinese Taipei for Olympic games.svg Chinese Taipei 1 0 1 2
File:Flag of Spain.svg Spain 1 0 1 2
File:Flag of Australia (converted).svg Australia 0 1 1 2
File:Flag of Singapore.svg Singapore 0 1 1 2
File:Flag of the Czech Republic.svg Czech Republic 0 1 0 1
File:Flag of Poland.svg Poland 0 1 0 1
File:Flag of Hong Kong.svg Hong Kong 0 0 1 1
File:Flag of Switzerland (Pantone).svg  Switzerland 0 1 0 1

Overgraduate Division

File:IGEM Grand Prize Winners Overgrad 2019.svg
Grand Prize Winners by Country/Region - Overgrad (as of November 2024).Page Template:Legend/styles.css has no content.
  1 Title
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  4 Titles
Top Overgraduate Teams by Year
Grand Prize 2nd 3rd Complete Results
2025 Brno Template:Flagicon Heidelberg Template:Flagicon iGEM 2025
2024 Marburg Template:Flagicon Aachen Template:Flagicon iGEM 2024
2023 Estonia-TUIT Template:Flagicon Leiden Template:Flagicon iGEM 2023
2022 UCopenhagen Template:Flagicon Montpellier Template:Flagicon iGEM 2022
2021 MarburgTemplate:Flagicon TU Delft Template:Flagicon iGEM 2021
2020 Leiden Template:Flagicon AachenTemplate:Flagicon iGEM 2020
2019 EPFL Template:Flagicon Wageningen UR Template:Flagicon iGEM 2019
2018 Marburg Template:Flagicon Munich Template:Flagicon iGEM 2018[permanent dead link]
2017 TU Delft Template:Flagicon Munich Template:Flagicon[note 7] iGEM 2017
2016 Munich Template:Flagicon[note 8] Wageningen UR Template:Flagicon iGEM 2016
2015 TU Delft Template:Flagicon BGU Israel Template:Flagicon iGEM 2015
2014 UC Davis Template:Flagicon Wageningen Template:Flagicon TU Darmstadt Template:Flagicon iGEM 2014
2013 Paris Bettencourt Template:Flagicon Bielefeld Template:Flagicon Sun Yat-sen Template:Flagicon iGEM 2013[note 9]
2012 Years prior to 2013 had no separate overgraduate division.

Overgraduate Ranking by Country

Country Grand Prize Runners-up Top 2 Total
File:Flag of Germany.svg Germany 4 6 10
File:Flag of the Netherlands.svg Netherlands 3 5 8
File:Flag of France.svg France 1 1 2
File:Flag of the Czech Republic.svg Czech 1 0 1
File:Flag of Denmark.svg Denmark 1 0 1
File:Flag of Estonia.svg Estonia 1 0 1
File:Flag of Switzerland (Pantone).svg  Switzerland 1 0 1
File:Flag of the United States.svg United States 1 0 1
File:Flag of Israel.svg Israel 0 1 1

Notes

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References

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  1. ^ Page Module:Citation/CS1/styles.css has no content."iGEM Competitions". igem.org. Retrieved 2023-04-25.
  2. ^ Page Module:Citation/CS1/styles.css has no content."Learn about iGEM". Retrieved 2013-05-06.
  3. ^ Page Module:Citation/CS1/styles.css has no content.Trafton, Anne. "Rewiring Cells". Technology Review.
  4. ^ Page Module:Citation/CS1/styles.css has no content."iGEM 2005". Retrieved 2013-05-06.
  5. ^ Page Module:Citation/CS1/styles.css has no content."Previous iGEM Competitions". iGEM. Retrieved 2011-11-12.
  6. ^ Page Module:Citation/CS1/styles.css has no content."What is iGEM? (part 3) - Insights from iGEM's History". iGEM Blog. 7 June 2023.
  7. ^ Page Module:Citation/CS1/styles.css has no content.Rettberg, R.; Dally, W.J.; Culler, D.E. (1998). "The Bleeding Edge". IEEE Micro. 18. IEEE: 10–11. doi:10.1109/MM.1998.653009.
  8. ^ Page Module:Citation/CS1/styles.css has no content."Team List 2011". iGEM. Retrieved 18 October 2014.
  9. ^ Page Module:Citation/CS1/styles.css has no content."Jamborees". iGEM. Retrieved 18 October 2014.
  10. ^ Page Module:Citation/CS1/styles.css has no content."Tracks 2014". iGEM. Retrieved 24 October 2014.
  11. ^ Page Module:Citation/CS1/styles.css has no content."Giant Jamboree". iGEM. Retrieved 24 October 2014.
  12. ^ Page Module:Citation/CS1/styles.css has no content.Guan, Zheng-jun; Schmidt, Markus; Pei, Lei; Wei, Wei; Ma, Ke-Ping (2013). "Biosafety Considerations of Synthetic Biology in the International Genetically Engineered Machine (iGEM) Competition". BioScience. 63: 25–34. doi:10.1525/bio.2013.63.1.7.

Further reading


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