Iodophenpropit
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| IUPAC name
3-(1H-imidazol-5-yl)propyl N'-[2-(4-iodophenyl)ethyl]imidothiocarbamate
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| Other names
1-[3-(3H-imidazol-4-yl)propylthio]-N'-[2-(4-iodophenyl)ethyl]formamidine
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3D model (JSmol)
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| MeSH | Iodophenpropit |
PubChem CID
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| Properties | |
| C15H19IN4S | |
| Molar mass | 414.30763 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Template:Chembox Footer/trackingTemplate:Short description
Iodophenpropit is a histamine antagonist which binds selectively to the H3 subtype. Its 125I radiolabelled form has been used for mapping the distribution of H3 receptors in animal studies.[1][2]
References
- ^ Page Module:Citation/CS1/styles.css has no content.Jansen, FP; Wu, TS; Voss, HP; Steinbusch, HW; Vollinga, RC; Rademaker, B; Bast, A; Timmerman, H (1994). "Characterization of the binding of the first selective radiolabelled histamine H3-receptor antagonist, 125I-iodophenpropit, to rat brain". British Journal of Pharmacology. 113 (2): 355–62. doi:10.1111/j.1476-5381.1994.tb16995.x. PMC 1510107. PMID 7834183.
- ^ Page Module:Citation/CS1/styles.css has no content.Jansen, FP; Mochizuki, T; Maeyama, K; Leurs, R; Timmerman, H (2000). "Characterization of histamine H3 receptors in mouse brain using the H3 antagonist 125Iiodophenpropit". Naunyn-Schmiedeberg's Archives of Pharmacology. 362 (1): 60–7. doi:10.1007/s002100000227. PMID 10935534. S2CID 21293180.
