KRT78
An Error has occurred retrieving Wikidata item for infobox Keratin, type II cytoskeletal 78 is a protein that in humans is encoded by the KRT78 gene.[1][2]
This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.[2]
References
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- ^ Page Module:Citation/CS1/styles.css has no content.Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
- ^ a b Page Module:Citation/CS1/styles.css has no content."Entrez Gene: KRT78 keratin 78".
Further reading
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- Page Module:Citation/CS1/styles.css has no content.Coulombe PA, Omary MB (2002). "'Hard' and 'soft' principles defining the structure, function and regulation of keratin intermediate filaments". Curr. Opin. Cell Biol. 14 (1): 110–22. doi:10.1016/S0955-0674(01)00301-5. PMID 11792552.
- Page Module:Citation/CS1/styles.css has no content.Mischke D, Wild G (1987). "Polymorphic keratins in human epidermis". J. Invest. Dermatol. 88 (2): 191–7. doi:10.1111/1523-1747.ep12525329. PMID 2433356.
- Page Module:Citation/CS1/styles.css has no content.Rogers MA, Winter H, Langbein L, et al. (2000). "Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain". J. Invest. Dermatol. 114 (3): 464–72. doi:10.1046/j.1523-1747.2000.00910.x. PMID 10692104.
- Page Module:Citation/CS1/styles.css has no content.Hesse M, Magin TM, Weber K (2002). "Genes for intermediate filament proteins and the draft sequence of the human genome: novel keratin genes and a surprisingly high number of pseudogenes related to keratin genes 8 and 18". J. Cell Sci. 114 (Pt 14): 2569–75. doi:10.1242/jcs.114.14.2569. PMID 11683385.
- Page Module:Citation/CS1/styles.css has no content.Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Page Module:Citation/CS1/styles.css has no content.Hesse M, Zimek A, Weber K, Magin TM (2004). "Comprehensive analysis of keratin gene clusters in humans and rodents". Eur. J. Cell Biol. 83 (1): 19–26. doi:10.1078/0171-9335-00354. hdl:11858/00-001M-0000-0012-EE54-6. PMID 15085952.
- Page Module:Citation/CS1/styles.css has no content.Rogers MA, Edler L, Winter H, et al. (2005). "Characterization of new members of the human type II keratin gene family and a general evaluation of the keratin gene domain on chromosome 12q13.13". J. Invest. Dermatol. 124 (3): 536–44. doi:10.1111/j.0022-202X.2004.23530.x. PMID 15737194.
- Page Module:Citation/CS1/styles.css has no content.Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Page Module:Citation/CS1/styles.css has no content.Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
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