MST1R
From Wikipedia, the free encyclopedia
Template:Short description An Error has occurred retrieving Wikidata item for infobox Macrophage-stimulating protein receptor is a protein that in humans is encoded by the MST1R gene.[1][2] MST1R is also known as RON (Recepteur d'Origine Nantais) kinase, named after the French city in which it was discovered. It is related to the c-MET receptor tyrosine kinase.[1][3]
Interactions
MST1R has been shown to interact with Grb2.[4][5]
References
Page Template:Reflist/styles.css has no content.
- ^ a b Page Module:Citation/CS1/styles.css has no content.Ronsin C, Muscatelli F, Mattei MG, Breathnach R (May 1993). "A novel putative receptor protein tyrosine kinase of the met family". Oncogene. 8 (5): 1195–202. PMID 8386824.
- ^ Page Module:Citation/CS1/styles.css has no content."Entrez Gene: MST1R macrophage stimulating 1 receptor (c-met-related tyrosine kinase)".
- ^ Page Module:Citation/CS1/styles.css has no content.Gaudino G, Follenzi A, Naldini L, Collesi C, Santoro M, Gallo KA, Godowski PJ, Comoglio PM (August 1994). "RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP". EMBO J. 13 (15): 3524–32. doi:10.1002/j.1460-2075.1994.tb06659.x. PMC 395256. PMID 8062829.
- ^ Page Module:Citation/CS1/styles.css has no content.Li BQ, Wang MH, Kung HF, Ronsin C, Breathnach R, Leonard EJ, Kamata T (November 1995). "Macrophage-stimulating protein activates Ras by both activation and translocation of SOS nucleotide exchange factor". Biochem. Biophys. Res. Commun. 216 (1): 110–8. Bibcode:1995BBRC..216..110L. doi:10.1006/bbrc.1995.2598. PMID 7488076.
- ^ Page Module:Citation/CS1/styles.css has no content.Iwama A, Yamaguchi N, Suda T (November 1996). "STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor family". EMBO J. 15 (21): 5866–75. doi:10.1002/j.1460-2075.1996.tb00973.x. PMC 452340. PMID 8918464.
Further reading
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- Page Module:Citation/CS1/styles.css has no content.Li BQ, Wang MH, Kung HF, et al. (1995). "Macrophage-stimulating protein activates Ras by both activation and translocation of SOS nucleotide exchange factor". Biochem. Biophys. Res. Commun. 216 (1): 110–8. Bibcode:1995BBRC..216..110L. doi:10.1006/bbrc.1995.2598. PMID 7488076.
- Page Module:Citation/CS1/styles.css has no content.Wang MH, Ronsin C, Gesnel MC, et al. (1994). "Identification of the ron gene product as the receptor for the human macrophage stimulating protein". Science. 266 (5182): 117–9. Bibcode:1994Sci...266..117W. doi:10.1126/science.7939629. PMID 7939629.
- Page Module:Citation/CS1/styles.css has no content.Gaudino G, Follenzi A, Naldini L, et al. (1994). "RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP". EMBO J. 13 (15): 3524–32. doi:10.1002/j.1460-2075.1994.tb06659.x. PMC 395256. PMID 8062829.
- Page Module:Citation/CS1/styles.css has no content.Lee ST, Strunk KM, Spritz RA (1993). "A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes". Oncogene. 8 (12): 3403–10. PMID 8247543.
- Page Module:Citation/CS1/styles.css has no content.Collesi C, Santoro MM, Gaudino G, Comoglio PM (1996). "A splicing variant of the RON transcript induces constitutive tyrosine kinase activity and an invasive phenotype". Mol. Cell. Biol. 16 (10): 5518–26. doi:10.1128/MCB.16.10.5518. PMC 231551. PMID 8816464.
- Page Module:Citation/CS1/styles.css has no content.Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
- Page Module:Citation/CS1/styles.css has no content.Iwama A, Yamaguchi N, Suda T (1997). "STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor family". EMBO J. 15 (21): 5866–75. doi:10.1002/j.1460-2075.1996.tb00973.x. PMC 452340. PMID 8918464.
- Page Module:Citation/CS1/styles.css has no content.Sakamoto O, Iwama A, Amitani R, et al. (1997). "Role of macrophage-stimulating protein and its receptor, RON tyrosine kinase, in ciliary motility". J. Clin. Invest. 99 (4): 701–9. doi:10.1172/JCI119214. PMC 507853. PMID 9045873.
- Page Module:Citation/CS1/styles.css has no content.Follenzi A, Bakovic S, Gual P, et al. (2000). "Cross-talk between the proto-oncogenes Met and Ron". Oncogene. 19 (27): 3041–9. doi:10.1038/sj.onc.1203620. PMID 10871856.
- Page Module:Citation/CS1/styles.css has no content.Chen YQ, Zhou YQ, Fisher JH, Wang MH (2002). "Targeted expression of the receptor tyrosine kinase RON in distal lung epithelial cells results in multiple tumor formation: oncogenic potential of RON in vivo". Oncogene. 21 (41): 6382–6. doi:10.1038/sj.onc.1205783. PMID 12214279.
- Page Module:Citation/CS1/styles.css has no content.Chen YQ, Zhou YQ, Fu LH, et al. (2002). "Multiple pulmonary adenomas in the lung of transgenic mice overexpressing the RON receptor tyrosine kinase. Recepteur d'origine nantais". Carcinogenesis. 23 (11): 1811–9. doi:10.1093/carcin/23.11.1811. PMID 12419829.
- Page Module:Citation/CS1/styles.css has no content.Zhou YQ, He C, Chen YQ, et al. (2003). "Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: generation of different splicing RON variants and their oncogenic potential". Oncogene. 22 (2): 186–97. doi:10.1038/sj.onc.1206075. PMID 12527888.
- Page Module:Citation/CS1/styles.css has no content.Danilkovitch-Miagkova A, Duh FM, Kuzmin I, et al. (2003). "Hyaluronidase 2 negatively regulates RON receptor tyrosine kinase and mediates transformation of epithelial cells by jaagsiekte sheep retrovirus". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4580–5. Bibcode:2003PNAS..100.4580D. doi:10.1073/pnas.0837136100. PMC 153598. PMID 12676986.
- Page Module:Citation/CS1/styles.css has no content.Rampino T, Gregorini M, Soccio G, et al. (2003). "The Ron proto-oncogene product is a phenotypic marker of renal oncocytoma". Am. J. Surg. Pathol. 27 (6): 779–85. doi:10.1097/00000478-200306000-00008. PMID 12766581. S2CID 21112098.
- Page Module:Citation/CS1/styles.css has no content.Penengo L, Rubin C, Yarden Y, Gaudino G (2003). "c-Cbl is a critical modulator of the Ron tyrosine kinase receptor". Oncogene. 22 (24): 3669–79. doi:10.1038/sj.onc.1206585. PMID 12802274.
- Page Module:Citation/CS1/styles.css has no content.Maggiora P, Lorenzato A, Fracchioli S, et al. (2003). "The RON and MET oncogenes are co-expressed in human ovarian carcinomas and cooperate in activating invasiveness". Exp. Cell Res. 288 (2): 382–9. doi:10.1016/S0014-4827(03)00250-7. PMID 12915129.
- Page Module:Citation/CS1/styles.css has no content.Santoro MM, Gaudino G, Marchisio PC (2003). "The MSP receptor regulates alpha6beta4 and alpha3beta1 integrins via 14-3-3 proteins in keratinocyte migration". Dev. Cell. 5 (2): 257–71. doi:10.1016/S1534-5807(03)00201-6. PMID 12919677.
- Page Module:Citation/CS1/styles.css has no content.Angeloni D, Danilkovitch-Miagkova A, Miagkov A, et al. (2004). "The soluble sema domain of the RON receptor inhibits macrophage-stimulating protein-induced receptor activation". J. Biol. Chem. 279 (5): 3726–32. doi:10.1074/jbc.M309342200. PMID 14597639.
- Page Module:Citation/CS1/styles.css has no content.van den Akker E, van Dijk T, Parren-van Amelsvoort M, et al. (2004). "Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors". Blood. 103 (12): 4457–65. doi:10.1182/blood-2003-08-2713. PMID 14982882. S2CID 8097946.
- Page Module:Citation/CS1/styles.css has no content.Raeppel S, Gaudette G, et al. (2010). "Identification of a novel series of potent RON receptor tyrosine kinase inhibitors". Bioorg. Med. Chem. Lett. 20 (9): 2745–9. doi:10.1016/j.bmcl.2010.03.073. PMID 20363625.
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