MYT1
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Template:Short description Template:DMCA An Error has occurred retrieving Wikidata item for infobox Myelin transcription factor 1 is a protein that in humans is encoded by the MYT1 gene.[1][2][3]
Function
The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system.[3]
Interactive pathway map
Template:MECP2andAssociatedRettSyndrome WP3584
Interactions
MYT1 has been shown to interact with PIN1.[4]
References
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- ^ Page Module:Citation/CS1/styles.css has no content.Kim JG, Hudson LD (December 1992). "Novel member of the zinc finger superfamily: A C2-HC finger that recognizes a glia-specific gene". Molecular and Cellular Biology. 12 (12): 5632–9. doi:10.1128/mcb.12.12.5632. PMC 360502. PMID 1280325.
- ^ Page Module:Citation/CS1/styles.css has no content.Booher RN, Holman PS, Fattaey A (August 1997). "Human Myt1 is a cell cycle-regulated kinase that inhibits Cdc2 but not Cdk2 activity". The Journal of Biological Chemistry. 272 (35): 22300–6. doi:10.1074/jbc.272.35.22300. PMID 9268380.
- ^ a b Page Module:Citation/CS1/styles.css has no content."Entrez Gene: MYT1 myelin transcription factor 1".
- ^ Page Module:Citation/CS1/styles.css has no content.Wells NJ, Watanabe N, Tokusumi T, Jiang W, Verdecia MA, Hunter T (October 1999). "The C-terminal domain of the Cdc2 inhibitory kinase Myt1 interacts with Cdc2 complexes and is required for inhibition of G(2)/M progression". Journal of Cell Science. 112 (19): 3361–71. doi:10.1242/jcs.112.19.3361. PMID 10504341.
Further reading
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- Page Module:Citation/CS1/styles.css has no content.Gogate N, Verma L, Zhou JM, Milward E, Rusten R, O'Connor M, Kufta C, Kim J, Hudson L, Dubois-Dalcq M (August 1994). "Plasticity in the adult human oligodendrocyte lineage". The Journal of Neuroscience. 14 (8): 4571–87. doi:10.1523/JNEUROSCI.14-08-04571.1994. PMC 6577192. PMID 7519254.
- Page Module:Citation/CS1/styles.css has no content.Armstrong RC, Kim JG, Hudson LD (August 1995). "Expression of myelin transcription factor I (MyTI), a "zinc-finger" DNA-binding protein, in developing oligodendrocytes". Glia. 14 (4): 303–21. doi:10.1002/glia.440140407. PMID 8530187. S2CID 38779689.
- Page Module:Citation/CS1/styles.css has no content.Liu F, Stanton JJ, Wu Z, Piwnica-Worms H (February 1997). "The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex". Molecular and Cellular Biology. 17 (2): 571–83. doi:10.1128/mcb.17.2.571. PMC 231782. PMID 9001210.
- Page Module:Citation/CS1/styles.css has no content.Kim JG, Armstrong RC, v Agoston D, Robinsky A, Wiese C, Nagle J, Hudson LD (October 1997). "Myelin transcription factor 1 (Myt1) of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system". Journal of Neuroscience Research. 50 (2): 272–90. doi:10.1002/(SICI)1097-4547(19971015)50:2<272::AID-JNR16>3.0.CO;2-A. PMID 9373037. S2CID 37120295.
- Page Module:Citation/CS1/styles.css has no content.Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (December 1998). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485.
- Page Module:Citation/CS1/styles.css has no content.Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (June 1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851.
- Page Module:Citation/CS1/styles.css has no content.Hirayama A, Oka A, Ito M, Tanaka F, Okoshi Y, Takashima S (January 2003). "Myelin transcription factor 1 (MyT1) immunoreactivity in infants with periventricular leukomalacia". Brain Research. Developmental Brain Research. 140 (1): 85–92. doi:10.1016/S0165-3806(02)00585-0. PMID 12524179.
- Page Module:Citation/CS1/styles.css has no content.Nielsen JA, Berndt JA, Hudson LD, Armstrong RC (January 2004). "Myelin transcription factor 1 (Myt1) modulates the proliferation and differentiation of oligodendrocyte lineage cells". Molecular and Cellular Neurosciences. 25 (1): 111–23. doi:10.1016/j.mcn.2003.10.001. PMID 14962745. S2CID 28151272.
- Page Module:Citation/CS1/styles.css has no content.Vana AC, Lucchinetti CF, Le TQ, Armstrong RC (May 2007). "Myelin transcription factor 1 (Myt1) expression in demyelinated lesions of rodent and human CNS". Glia. 55 (7): 687–97. doi:10.1002/glia.20492. PMC 2789289. PMID 17330875.
External links
- MYT1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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