Megasphaera

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Megasphaera is a genus of Bacillota bacteria classified within the class Negativicutes.[1][2] Several species in the genus, including M. elsdenii and M. hexanoica, are known to utilize lactate.[3]

This classification has been reexamined.[4] This genus appears to be a member of the Clostridia.

Phylogeny

The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN)[1] and National Center for Biotechnology Information (NCBI).[2]

16S rRNA based LTP_10_2024[5][6][7] 120 marker proteins based GTDB 10-RS226[8][9][10]

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Unassigned species:

  • M. jansseni Heng et al. 2025
  • "M. vaginalis" Srinivasan et al. 2021 non Bordigoni et al. 2020

See also

References

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  1. ^ a b c Template:Lpsn3
  2. ^ a b Page Module:Citation/CS1/styles.css has no content.Schoch CL; et al. "Megasphaera". National Center for Biotechnology Information (NCBI) taxonomy database. Retrieved 2025-06-05.
  3. ^ Page Module:Citation/CS1/styles.css has no content.Strachan, CR.; et al. (2025). "Distinct lactate utilization strategies drive niche differentiation between two co-existing Megasphaera species in the rumen microbiome". The ISME Journal. 19 (1) wraf147. doi:10.1093/ismejo/wraf147. PMC 12342382.
  4. ^ Yutin N, Galperin MY (2013) A genomic update on Clostridial phylogeny: Gram-negative spore formers and other misplaced Clostridia. Environ Microbiol doi: 10.1111/1462-2920.12173
  5. ^ Page Module:Citation/CS1/styles.css has no content."The LTP". Retrieved 10 December 2024.
  6. ^ Page Module:Citation/CS1/styles.css has no content."LTP_all tree in newick format". Retrieved 10 December 2024.
  7. ^ Page Module:Citation/CS1/styles.css has no content."LTP_10_2024 Release Notes" (PDF). Retrieved 10 December 2024.
  8. ^ Page Module:Citation/CS1/styles.css has no content."GTDB release 10-RS226". Genome Taxonomy Database. Retrieved 1 May 2025.
  9. ^ Page Module:Citation/CS1/styles.css has no content."bac120_r226.sp_label". Genome Taxonomy Database. Retrieved 1 May 2025.
  10. ^ Page Module:Citation/CS1/styles.css has no content."Taxon History". Genome Taxonomy Database. Retrieved 1 May 2025.
  • Arik, H. D., Gulsen, N., Hayirli, A., & Alatas, M. S. (2019). Efficacy of Megasphaera elsdenii inoculation in subacute ruminal acidosis in cattle. Journal of animal physiology and animal nutrition, 103(2), 416–426.

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