Methoserpidine

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Methoserpidine
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Names
IUPAC name
Methyl 10,17α-dimethoxy-18β-[(3,4,5-trimethoxybenzoyl)oxy]-3β,20α-yohimban-16β-carboxylate
Systematic IUPAC name
Methyl (1S,2R,3R,4aS,13bR,14aS)-2,10-dimethoxy-3-[(3,4,5-trimethoxybenzoyl)oxy]-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2′,3′:3,4]pyrido[1,2-b]isoquinoline-1-carboxylate
Identifiers
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3D model (JSmol)
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  • InChI=1S/C33H40N2O9/c1-38-19-7-8-23-22(14-19)20-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)21(18)15-24(35)29(20)34-23/h7-8,11-12,14,18,21,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,21+,24-,27-,28+,31+/m1/s1 ☒N
    Key: ULBNWNUHGJLQHO-VKMIBBQISA-N ☒N
  • InChI=1/C33H40N2O9/c1-38-19-7-8-23-22(14-19)20-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)21(18)15-24(35)29(20)34-23/h7-8,11-12,14,18,21,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,21+,24-,27-,28+,31+/m1/s1
    Key: ULBNWNUHGJLQHO-VKMIBBQIBR
  • CO[C@H]1[C@@H](C[C@@H]2CN3CCC4=C([C@H]3C[C@@H]2[C@@H]1C(=O)OC)NC5=C4C=C(C=C5)OC)OC(=O)C6=CC(=C(C(=C6)OC)OC)OC
Properties
C33H40N2O9
Molar mass 608.688 g·mol−1
Pharmacology
C02AA06 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

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Methoserpidine is an antihypertensive drug related to reserpine.[1]

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content.Jones, D. L.; Michael, A. M.; Ommer, J. P. (1961). "Clinical Trial of Methoserpidine in General Practice". British Medical Journal. 2 (5269): 1738–1741. doi:10.1136/bmj.2.5269.1738. PMC 1970934. PMID 14452236.

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