Morinamide

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Morinamide
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Clinical data
Trade namesPiazolina
AHFS/Drugs.comInternational Drug Names
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Legal status
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Identifiers
  • N-(morpholin-4-ylmethyl)pyrazine-2-carboxamide
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Chemical and physical data
FormulaC10H14N4O2
Molar mass222.248 g·mol−1
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  • O=C(NCN1CCOCC1)c1cnccn1
  • InChI=1S/C10H14N4O2/c15-10(9-7-11-1-2-12-9)13-8-14-3-5-16-6-4-14/h1-2,7H,3-6,8H2,(H,13,15)
  • Key:GVTLAVKAVSKBKK-UHFFFAOYSA-N
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Morinamide (or morphazinamide, or morinamid) is a drug used in the treatment of tuberculosis.[2] Although morphazinamide is metabolized to pyrazinamide within the body,[3] the drug itself has intrinsic in vitro activity.[4]

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content.Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in português do Brasil). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
  2. ^ Page Module:Citation/CS1/styles.css has no content.Bonanni G, Ciccariello M, Mancini P, Pace V, Sagliaschi G (1993). "Concomitant ceco-appendicular and urinary tuberculosis. Description of two rare cases: physiopathological and diagnostic remarks". Riv Eur Sci Med Farmacol. 15 (3–4): 171–174. PMID 7761665.
  3. ^ Page Module:Citation/CS1/styles.css has no content.Trnka L, Kuška J, Havel A (1964). "Comparison of the Antituberculous Activity of Morphazinamide and Pyrazinamide on Chronic Experimental Tuberculosis. I. The Antimycobacterial Efficacy made in vitro and in vivo". Chemotherapia. 9 (3): 158–167. doi:10.1159/000220356. PMID 4953657.
  4. ^ Page Module:Citation/CS1/styles.css has no content.Carrada Bravo T, Ellard G, Mitchison D, Horsfall P (1975). "Reappraisal of the activity of morphazinamide against M. tuberculosis". Tubercle. 56 (3): 211–217. doi:10.1016/0041-3879(75)90054-9. PMID 814663.

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