NFIL3
Template:Short description Template:Cs1 config An Error has occurred retrieving Wikidata item for infobox Nuclear factor, interleukin 3 regulated, also known as NFIL3 or E4BP4 is a protein which in humans is encoded by the NFIL3 gene.[1]
Function
Expression of interleukin-3 (IL-3) is restricted to activated T cells, natural killer (NK) cells, and mast cell lines. Transcription initiation depends on the activating capacity of specific protein factors, such as NFIL3, that bind to regulatory regions of the gene, usually upstream of the transcription start site.[1][2]
References
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- ^ a b Page Module:Citation/CS1/styles.css has no content."Entrez Gene: NFIL3 nuclear factor, interleukin 3 regulated".
- ^ Page Module:Citation/CS1/styles.css has no content.Zhang W, Zhang J, Kornuc M, Kwan K, Frank R, Nimer SD (November 1995). "Molecular cloning and characterization of NF-IL3A, a transcriptional activator of the human interleukin-3 promoter". Molecular and Cellular Biology. 15 (11): 6055–63. doi:10.1128/mcb.15.11.6055. PMC 230857. PMID 7565758.
Further reading
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- Page Module:Citation/CS1/styles.css has no content.Cowell IG, Skinner A, Hurst HC (July 1992). "Transcriptional repression by a novel member of the bZIP family of transcription factors". Molecular and Cellular Biology. 12 (7): 3070–7. doi:10.1128/mcb.12.7.3070. PMC 364521. PMID 1620116.
- Page Module:Citation/CS1/styles.css has no content.Zhang W, Zhang J, Kornuc M, Kwan K, Frank R, Nimer SD (November 1995). "Molecular cloning and characterization of NF-IL3A, a transcriptional activator of the human interleukin-3 promoter". Molecular and Cellular Biology. 15 (11): 6055–63. doi:10.1128/mcb.15.11.6055. PMC 230857. PMID 7565758.
- Page Module:Citation/CS1/styles.css has no content.Matoba R, Okubo K, Hori N, Fukushima A, Matsubara K (September 1994). "The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression". Gene. 146 (2): 199–207. doi:10.1016/0378-1119(94)90293-3. PMID 8076819.
- Page Module:Citation/CS1/styles.css has no content.Cowell IG, Hurst HC (September 1996). "Protein-protein interaction between the transcriptional repressor E4BP4 and the TBP-binding protein Dr1". Nucleic Acids Research. 24 (18): 3607–13. doi:10.1093/nar/24.18.3607. PMC 146135. PMID 8836190.
- Page Module:Citation/CS1/styles.css has no content.Ikushima S, Inukai T, Inaba T, Nimer SD, Cleveland JL, Look AT (March 1997). "Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes". Proceedings of the National Academy of Sciences of the United States of America. 94 (6): 2609–14. Bibcode:1997PNAS...94.2609I. doi:10.1073/pnas.94.6.2609. PMC 20136. PMID 9122243.
- Page Module:Citation/CS1/styles.css has no content.Hulme DJ, Blair IP, Dawkins JL, Nicholson GA (June 2000). "Exclusion of NFIL3 as the gene causing hereditary sensory neuropathy type I by mutation analysis". Human Genetics. 106 (6): 594–6. doi:10.1007/s004390000306. PMID 10942106.
- Page Module:Citation/CS1/styles.css has no content.Ozkurt IC, Tetradis S (July 2003). "Parathyroid hormone-induced E4BP4/NFIL3 down-regulates transcription in osteoblasts". The Journal of Biological Chemistry. 278 (29): 26803–9. doi:10.1074/jbc.M212652200. PMID 12743120.
- Page Module:Citation/CS1/styles.css has no content.Priceman SJ, Kirzner JD, Nary LJ, Morris D, Shankar DB, Sakamoto KM, Medh RD (June 2006). "Calcium-dependent upregulation of E4BP4 expression correlates with glucocorticoid-evoked apoptosis of human leukemic CEM cells". Biochemical and Biophysical Research Communications. 344 (2): 491–9. Bibcode:2006BBRC..344..491P. doi:10.1016/j.bbrc.2006.03.169. PMC 2763529. PMID 16630563.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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