Octadecanoid pathway

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File:Jasmonic acid structure.png
Jasmonic acid
File:ALAnumbering.svg
Alpha-linolenic acid

The octadecanoid pathway is a biosynthetic pathway for the production of the phytohormone jasmonic acid (JA), an important hormone for induction of defense genes. JA is synthesized from alpha-linolenic acid, which can be released from the plasma membrane by certain lipase enzymes. For example, in the wound defense response, phospholipase C will cause the release of alpha-linolenic acid for JA synthesis.

In the first step, alpha-linolenic acid is oxidized by the enzyme lipoxygenase. This forms 13-hydroperoxylinolenic acid, which is then modified by a dehydrase and undergoes cyclization by allene oxide cyclase to form 12-oxo-phytodienoic acid. This undergoes reduction and three rounds of beta oxidation to form jasmonic acid.[1]

Footnotes

  1. ^ Page Module:Citation/CS1/styles.css has no content."Jasmonic Acid Synthesis". Archived from the original on 2012-02-06. Retrieved 2007-01-19.

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