Protionamide

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Protionamide
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Clinical data
AHFS/Drugs.comInternational Drug Names
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Identifiers
  • 2-propylpyridine-4-carbothioamide
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Chemical and physical data
FormulaC9H12N2S
Molar mass180.27 g·mol−1
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  • CCCc1cc(ccn1)C(=S)N
  • InChI=1S/C9H12N2S/c1-2-3-8-6-7(9(10)12)4-5-11-8/h4-6H,2-3H2,1H3,(H2,10,12) ☒N
  • Key:VRDIULHPQTYCLN-UHFFFAOYSA-N ☒N
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Protionamide (or prothionamide) is a medication used in the treatment of tuberculosis and leprosy.[1][2]

Protionamide is a therapeutic alternative on the World Health Organization's List of Essential Medicines.[3]

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content.Wang F, Langley R, Gulten G, Dover LG, Besra GS, Jacobs WR, et al. (January 2007). "Mechanism of thioamide drug action against tuberculosis and leprosy". The Journal of Experimental Medicine. 204 (1): 73–8. doi:10.1084/jem.20062100. PMC 2118422. PMID 17227913.
  2. ^ Page Module:Citation/CS1/styles.css has no content.Fajardo TT, Guinto RS, Cellona RV, Abalos RM, Dela Cruz EC, Gelber RH (March 2006). "A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy". The American Journal of Tropical Medicine and Hygiene. 74 (3): 457–61. doi:10.4269/ajtmh.2006.74.457. PMID 16525107.
  3. ^ Page Module:Citation/CS1/styles.css has no content.The selection and use of essential medicines, 2025: WHO Model List of Essential Medicines, 24th list. Geneva: World Health Organization. 2025. doi:10.2471/B09474. hdl:10665/382243.

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