Protohepanvirus

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Protohepanvirus is a genus of viruses that belongs to the Hepanvirinae subfamily of the family Parvoviridae. Insects and shrimps serve as natural hosts. Infection leads to mortality in the early larval and postlarval stages of the shrimp.[1] There is only one species in this genus: Fenneropenaeus chinensis hepatopancreatic densovirus (Protohepanvirus decapod1).[2][3]

Structure

Viruses in genus Protohepanvirus are non-enveloped, with T=1 icosahedral symmetry and round geometries. The diameter is around 21-22 nm. Genomes are linear, around 6kb in length.[1][4]

Genus Structure Symmetry Capsid Genomic arrangement Genomic segmentation
Protohepanvirus Icosahedral T=1 Non-enveloped Linear Segmented

Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment to host receptors, which mediate clathrin-mediated endocytosis. Replication follows the rolling-hairpin model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear pore export. Insects and shrimps serve as the natural host.[1][4]

Genus Host details Tissue tropism Entry details Release details Replication site Assembly site Transmission
Protohepanvirus Crustaceans None Clathrin-mediated endocytosis Budding Nucleus Nucleus Unknown

References

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  1. ^ a b c Page Module:Citation/CS1/styles.css has no content."Viral Zone". ExPASy. Retrieved 13 August 2015.
  2. ^ Page Module:Citation/CS1/styles.css has no content."Virus Taxonomy: 2025 Release". International Committee on Taxonomy of Viruses. Retrieved 21 March 2026.
  3. ^ Page Module:Citation/CS1/styles.css has no content."Species List: Parvoviridae". International Committee on Taxonomy of Viruses. Retrieved 21 March 2026.
  4. ^ a b Page Module:Citation/CS1/styles.css has no content."ICTV 10th Report (2018) Parvoviridae".

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