RASSF2
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Template:Short description An Error has occurred retrieving Wikidata item for infobox Ras association domain-containing protein 2 is a protein that in humans is encoded by the RASSF2 gene.[1][2][3]
This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported.[3]
Interactions
RASSF2 has been shown to interact with KRAS.[4]
References
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- ^ Page Module:Citation/CS1/styles.css has no content.Nagase T, Seki N, Ishikawa K, Tanaka A, Nomura N (Nov 1996). "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 3 (1): 17–24. doi:10.1093/dnares/3.1.17. PMID 8724849.
- ^ Page Module:Citation/CS1/styles.css has no content.Hesson LB, Wilson R, Morton D, Adams C, Walker M, Maher ER, Latif F (Jun 2005). "CpG island promoter hypermethylation of a novel Ras-effector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutations". Oncogene. 24 (24): 3987–94. doi:10.1038/sj.onc.1208566. PMID 15806169.
- ^ a b Page Module:Citation/CS1/styles.css has no content."Entrez Gene: RASSF2 Ras association (RalGDS/AF-6) domain family 2".
- ^ Page Module:Citation/CS1/styles.css has no content.Vos, Michele D; Ellis Chad A; Elam Candice; Ulku Aylin S; Taylor Barbara J; Clark Geoffrey J (Jul 2003). "RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor". J. Biol. Chem. 278 (30). United States: 28045–51. doi:10.1074/jbc.M300554200. ISSN 0021-9258. PMID 12732644.
Further reading
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- Page Module:Citation/CS1/styles.css has no content.Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Page Module:Citation/CS1/styles.css has no content.Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Page Module:Citation/CS1/styles.css has no content.Comincini S, Castiglioni BM, Foti GM, et al. (2001). "Isolation and molecular characterization of rasfadin, a novel gene in the vicinity of the bovine prion gene". Mamm. Genome. 12 (2): 150–6. doi:10.1007/s003350010239. PMID 11210185. S2CID 11824136.
- Page Module:Citation/CS1/styles.css has no content.Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
- Page Module:Citation/CS1/styles.css has no content.Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Page Module:Citation/CS1/styles.css has no content.Vos MD, Ellis CA, Elam C, et al. (2003). "RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor". J. Biol. Chem. 278 (30): 28045–51. doi:10.1074/jbc.M300554200. PMID 12732644.
- Page Module:Citation/CS1/styles.css has no content.Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Page Module:Citation/CS1/styles.css has no content.Fujita H, Fukuhara S, Sakurai A, et al. (2005). "Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes". J. Biol. Chem. 280 (6): 5022–31. doi:10.1074/jbc.M409701200. PMID 15569673.
- Page Module:Citation/CS1/styles.css has no content.Akino K, Toyota M, Suzuki H, et al. (2005). "The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer". Gastroenterology. 129 (1): 156–69. doi:10.1053/j.gastro.2005.03.051. PMID 16012945.
- Page Module:Citation/CS1/styles.css has no content.Endoh M, Tamura G, Honda T, et al. (2006). "RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer". Br. J. Cancer. 93 (12): 1395–9. doi:10.1038/sj.bjc.6602854. PMC 2361541. PMID 16265349.
- Page Module:Citation/CS1/styles.css has no content.Zhang Z, Sun D, Van do N, et al. (2007). "Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma". Int. J. Cancer. 120 (1): 32–8. doi:10.1002/ijc.22185. hdl:10616/38128. PMID 17013896. S2CID 36204366.
- Page Module:Citation/CS1/styles.css has no content.Park HW, Kang HC, Kim IJ, et al. (2007). "Correlation between hypermethylation of the RASSF2A promoter and K-ras/BRAF mutations in microsatellite-stable colorectal cancers". Int. J. Cancer. 120 (1): 7–12. doi:10.1002/ijc.22276. PMID 17013898. S2CID 31478640.
- Page Module:Citation/CS1/styles.css has no content.Kumari G, Singhal PK, Rao MR, Mahalingam S (2007). "Nuclear transport of Ras-associated tumor suppressor proteins: different transport receptor binding specificities for arginine-rich nuclear targeting signals". J. Mol. Biol. 367 (5): 1294–311. doi:10.1016/j.jmb.2007.01.026. PMID 17320110.
- Page Module:Citation/CS1/styles.css has no content.Kaira K, Sunaga N, Tomizawa Y, et al. (2007). "Epigenetic inactivation of the RAS-effector gene RASSF2 in lung cancers". Int. J. Oncol. 31 (1): 169–73. doi:10.3892/ijo.31.1.169. PMID 17549418.
