RIPK4
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Template:Short description An Error has occurred retrieving Wikidata item for infobox Receptor-interacting serine/threonine-protein kinase 4 is an enzyme that in humans is encoded by the RIPK4 gene.[1][2]
The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.[2]
Interactions
RIPK4 has been shown to interact with PRKCB1.[3]
References
Page Template:Reflist/styles.css has no content.
- ^ Page Module:Citation/CS1/styles.css has no content.Hattori M, Fujiyama A, Taylor TD, Watanabe H, Yada T, Park HS, Toyoda A, Ishii K, Totoki Y, Choi DK, Groner Y, Soeda E, Ohki M, Takagi T, Sakaki Y, Taudien S, Blechschmidt K, Polley A, Menzel U, Delabar J, Kumpf K, Lehmann R, Patterson D, Reichwald K, Rump A, Schillhabel M, Schudy A, Zimmermann W, Rosenthal A, Kudoh J, Schibuya K, Kawasaki K, Asakawa S, Shintani A, Sasaki T, Nagamine K, Mitsuyama S, Antonarakis SE, Minoshima S, Shimizu N, Nordsiek G, Hornischer K, Brant P, Scharfe M, Schon O, Desario A, Reichelt J, Kauer G, Blocker H, Ramser J, Beck A, Klages S, Hennig S, Riesselmann L, Dagand E, Haaf T, Wehrmeyer S, Borzym K, Gardiner K, Nizetic D, Francis F, Lehrach H, Reinhardt R, Yaspo ML (June 2000). "The DNA sequence of human chromosome 21". Nature. 405 (6784): 311–9. Bibcode:2000Natur.405..311H. doi:10.1038/35012518. PMID 10830953.
- ^ a b Page Module:Citation/CS1/styles.css has no content."Entrez Gene: RIPK4 receptor-interacting serine-threonine kinase 4".
- ^ Page Module:Citation/CS1/styles.css has no content.Chen, L; Haider K; Ponda M; Cariappa A; Rowitch D; Pillai S (June 2001). "Protein kinase C-associated kinase (PKK), a novel membrane-associated, ankyrin repeat-containing protein kinase". J. Biol. Chem. 276 (24): 21737–44. doi:10.1074/jbc.M008069200. ISSN 0021-9258. PMID 11278382.
Further reading
Page Template:Refbegin/styles.css has no content.
- Page Module:Citation/CS1/styles.css has no content.Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
- Page Module:Citation/CS1/styles.css has no content.Bhr C, Rohwer A, Stempka L, et al. (2000). "DIK, a novel protein kinase that interacts with protein kinase Cdelta. Cloning, characterization, and gene analysis". J. Biol. Chem. 275 (46): 36350–7. doi:10.1074/jbc.M004771200. PMID 10948194.
- Page Module:Citation/CS1/styles.css has no content.Chen L, Haider K, Ponda M, et al. (2001). "Protein kinase C-associated kinase (PKK), a novel membrane-associated, ankyrin repeat-containing protein kinase". J. Biol. Chem. 276 (24): 21737–44. doi:10.1074/jbc.M008069200. PMID 11278382.
- Page Module:Citation/CS1/styles.css has no content.Meylan E, Martinon F, Thome M, et al. (2003). "RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF-κB and is processed during apoptosis". EMBO Rep. 3 (12): 1201–8. doi:10.1093/embo-reports/kvf236. PMC 1308326. PMID 12446564.
- Page Module:Citation/CS1/styles.css has no content.Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Page Module:Citation/CS1/styles.css has no content.Moran ST, Haider K, Ow Y, et al. (2003). "Protein kinase C-associated kinase can activate NFkappaB in both a kinase-dependent and a kinase-independent manner". J. Biol. Chem. 278 (24): 21526–33. doi:10.1074/jbc.M301575200. PMID 12676934.
- Page Module:Citation/CS1/styles.css has no content.Scanlan MJ, Gout I, Gordon CM, et al. (2003). "Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression". Cancer Immun. 1: 4. PMID 12747765.
- Page Module:Citation/CS1/styles.css has no content.Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Page Module:Citation/CS1/styles.css has no content.Adams S, Pankow S, Werner S, Munz B (2007). "Regulation of NF-kappaB activity and keratinocyte differentiation by the RIP4 protein: implications for cutaneous wound repair". J. Invest. Dermatol. 127 (3): 538–44. doi:10.1038/sj.jid.5700588. PMID 17039240.
External links
- RIPK4 human gene location in the UCSC Genome Browser.
- RIPK4 human gene details in the UCSC Genome Browser.
