RNR3
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RNR3 (RNA, ribosomal 45S cluster 3[1]) is a human ribosomal DNA gene located on Chromosome 15. Tandem copies of this gene form one of five nucleolus organizer regions in the human genome, they are located on the chromosomes 13 (RNR1), 14 (RNR2), 15 (RNR3), 21 (RNR4), 22 (RNR5).[2][1]
References
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- ^ a b Page Module:Citation/CS1/styles.css has no content."Entrez Gene: RNR1 RNA, ribosomal 3". Retrieved 2024-08-01.
- ^ Page Module:Citation/CS1/styles.css has no content.Schmidt, Olaf (2017). Fritsche, Olaf (ed.). Genetik und Molekularbiologie [Genetics and molecular biology]. Kompaktwissen Biologie (in German). Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg. doi:10.1007/978-3-662-50274-7. ISBN 978-3-662-50273-0.
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Further reading
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- Nucleolus organizer regions are chromosomal regions crucial for the formation of the nucleolus, located on the short arms of the acrocentric chromosomes 13, 14, 15, 21 and 22
- Page Module:Citation/CS1/styles.css has no content.Kern SE, Kinzler KW, Bruskin A, et al. (1991). "Identification of p53 as a sequence-specific DNA-binding protein". Science. 252 (5013): 1708–1711. Bibcode:1991Sci...252.1708K. doi:10.1126/science.2047879. PMID 2047879. S2CID 19647885.
- Page Module:Citation/CS1/styles.css has no content.Gonzalez IL, Chambers C, Gorski JL, et al. (1990). "Sequence and structure correlation of human ribosomal transcribed spacers". J. Mol. Biol. 212 (1): 27–35. doi:10.1016/0022-2836(90)90302-3. PMID 2319598.
- Page Module:Citation/CS1/styles.css has no content.Sylvester JE, Petersen R, Schmickel RD (1990). "Human ribosomal DNA: novel sequence organization in a 4.5-kb region upstream from the promoter". Gene. 84 (1): 193–196. doi:10.1016/0378-1119(89)90155-8. PMID 2606358.
- Page Module:Citation/CS1/styles.css has no content.La Volpe A, Simeone A, D'Esposito M, et al. (1985). "Molecular analysis of the heterogeneity region of the human ribosomal spacer". J. Mol. Biol. 183 (2): 213–223. doi:10.1016/0022-2836(85)90214-1. PMID 2989541.
- Page Module:Citation/CS1/styles.css has no content.Bartsch I, Schoneberg C, Grummt I (1987). "Evolutionary changes of sequences and factors that direct transcription termination of human and mouse ribsomal genes". Mol. Cell. Biol. 7 (7): 2521–2529. doi:10.1128/mcb.7.7.2521. PMC 365386. PMID 3649563.
- Page Module:Citation/CS1/styles.css has no content.Haltiner MM, Smale ST, Tjian R (1987). "Two distinct promoter elements in the human rRNA gene identified by linker scanning mutagenesis". Mol. Cell. Biol. 6 (1): 227–235. doi:10.1128/mcb.6.1.227. PMC 367502. PMID 3785147.
- Page Module:Citation/CS1/styles.css has no content.Gonzalez IL, Gorski JL, Campen TJ, et al. (1985). "Variation among human 28S ribosomal RNA genes". Proc. Natl. Acad. Sci. U.S.A. 82 (22): 7666–7670. Bibcode:1985PNAS...82.7666G. doi:10.1073/pnas.82.22.7666. PMC 391394. PMID 3865188.
- Page Module:Citation/CS1/styles.css has no content.McCallum FS, Maden BE (1986). "Human 18 S ribosomal RNA sequence inferred from DNA sequence. Variations in 18 S sequences and secondary modification patterns between vertebrates". Biochem. J. 232 (3): 725–733. doi:10.1042/bj2320725. PMC 1152944. PMID 4091818.
- Page Module:Citation/CS1/styles.css has no content.Financsek I, Mizumoto K, Mishima Y, Muramatsu M (1982). "Human ribosomal RNA gene: nucleotide sequence of the transcription initiation region and comparison of three mammalian genes". Proc. Natl. Acad. Sci. U.S.A. 79 (10): 3092–3096. Bibcode:1982PNAS...79.3092F. doi:10.1073/pnas.79.10.3092. PMC 346359. PMID 6954460.
- Page Module:Citation/CS1/styles.css has no content.Gonzalez IL, Sylvester JE (1995). "Complete sequence of the 43-kb human ribosomal DNA repeat: analysis of the intergenic spacer". Genomics. 27 (2): 320–328. doi:10.1006/geno.1995.1049. PMID 7557999.
- Page Module:Citation/CS1/styles.css has no content.Gonzalez IL, Sylvester JE (2001). "Human rDNA: evolutionary patterns within the genes and tandem arrays derived from multiple chromosomes". Genomics. 73 (3): 255–263. doi:10.1006/geno.2001.6540. PMID 11350117.
