Revaprazan

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Revaprazan
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Clinical data
Trade namesRevanex[1]
Other namesYH1885
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  • None
Identifiers
  • N-(4-Fluorophenyl)-4,5-dimethyl-6-(1-methyl-3,4-dihydro-2(1H)-isoquinolinyl)-2-pyrimidinamine
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Chemical and physical data
FormulaC22H23FN4
Molar mass362.452 g·mol−1
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  • c1cc(F)ccc1Nc2nc(C)c(C)c(n2)N3CCc4ccccc4C3C
  • InChI=1S/C22H23FN4/c1-14-15(2)24-22(25-19-10-8-18(23)9-11-19)26-21(14)27-13-12-17-6-4-5-7-20(17)16(27)3/h4-11,16H,12-13H2,1-3H3,(H,24,25,26)
  • Key:LECZXZOBEZITCL-UHFFFAOYSA-N
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Revaprazan (trade name Revanex) is a drug that reduces gastric acid secretion which is used for the treatment of gastritis.[2] It acts as an acid pump antagonist[3] (potassium-competitive acid blocker). Revaprazan is approved for use in South Korea,[4] but is not approved in Europe or the United States.

See also

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content."Revaprazan". drugs.com.
  2. ^ Page Module:Citation/CS1/styles.css has no content.Kim HK, Park SH, Cheung DY, Cho YS, Kim JI, Kim SS, Chae HS, Kim JK, Chung IS (Oct 2010). "Clinical trial: inhibitory effect of revaprazan on gastric acid secretion in healthy male subjects". J Gastroenterol Hepatol. 25 (10): 1618–1625. doi:10.1111/j.1440-1746.2010.06408.x. PMID 20880169. S2CID 41932174.
  3. ^ Page Module:Citation/CS1/styles.css has no content.Yu KS, Bae KS, Shon JH, Cho JY, Yi SY, Chung JY, Lim HS, Jang IJ, Shin SG, Song KS, Moon BS (Jan 2004). "Pharmacokinetic and pharmacodynamic evaluation of a novel proton pump inhibitor, YH1885, in healthy volunteers". J Clin Pharmacol. 44 (1): 73–82. doi:10.1177/0091270003261321. PMID 14681344. S2CID 19658496.
  4. ^ Page Module:Citation/CS1/styles.css has no content."Revaprazan Yuhan registered, South Korea (gastritis)". R & D Focus Drug News. September 25, 2006. Archived from the original on April 29, 2014.

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