SCN4B
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Template:Short description Template:Cs1 config An Error has occurred retrieving Wikidata item for infobox Sodium channel β-subunit 4, also known as SCN4B or Naβ4, is an auxiliary sodium channel subunit that can alter the kinetics of sodium channels.[1] The protein is encoded by the SCN4B gene.[2] Mutations in the SCN4B are associated with long QT syndrome.[3]
SCN4B might additionally function as a cell adhesion molecule.[4][5]
See also
References
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- ^ Page Module:Citation/CS1/styles.css has no content.Lewis AH, Raman IM (2014-11-15). "Resurgent current of voltage-gated Na+ channels". The Journal of Physiology. 592 (22): 4825–4838. doi:10.1113/jphysiol.2014.277582. ISSN 1469-7793. PMC 4259529. PMID 25172941.
- ^ Page Module:Citation/CS1/styles.css has no content."Entrez Gene: sodium channel".
- ^ Page Module:Citation/CS1/styles.css has no content.Medeiros-Domingo A, Kaku T, Tester DJ, Iturralde-Torres P, Itty A, Ye B, et al. (July 2007). "SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome". Circulation. 116 (2): 134–142. doi:10.1161/CIRCULATIONAHA.106.659086. PMC 3332546. PMID 17592081.
- ^ Page Module:Citation/CS1/styles.css has no content.Shimizu H (2016). "Structure-based site-directed photo-crosslinking analyses of multimeric cell-adhesive interactions of voltage-gated sodium channel β subunits". Scientific Reports. 6 26618. Bibcode:2016NatSR...626618S. doi:10.1038/srep26618. PMC 4877568. PMID 27216889.
- ^ Page Module:Citation/CS1/styles.css has no content.Shimizu H (2017). "Parallel homodimer structures of the extracellular domains of the voltage-gated sodium channel β4 subunit explain its role in cell-cell adhesion". J Biol Chem. 27 (32): 13428–13440. doi:10.1074/jbc.M117.786509. PMC 5555201. PMID 28655765.
Further reading
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- Page Module:Citation/CS1/styles.css has no content.Delgado P, GarcÃa-Zueco JC, Rubio-Félix D, Giralt M (1992). "[Idiopathic thrombocytopenic purpura: present knowledge and future expectations]". Sangre. 37 (6): 449–456. PMID 1293796.
- Page Module:Citation/CS1/styles.css has no content.Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
- Page Module:Citation/CS1/styles.css has no content.Yu FH, Westenbroek RE, Silos-Santiago I, et al. (2003). "Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2". J. Neurosci. 23 (20): 7577–7585. doi:10.1523/JNEUROSCI.23-20-07577.2003. PMC 6740763. PMID 12930796.
- Page Module:Citation/CS1/styles.css has no content.Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Page Module:Citation/CS1/styles.css has no content.Webb J, Wu FF, Cannon SC (2009). "Slow inactivation of the NaV1.4 sodium channel in mammalian cells is impeded by co-expression of the beta1 subunit". Pflügers Arch. 457 (6): 1253–1263. doi:10.1007/s00424-008-0600-8. PMC 6207185. PMID 18941776.
- Page Module:Citation/CS1/styles.css has no content.Shimizu H (2016). "Structure-based site-directed photo-crosslinking analyses of multimeric cell-adhesive interactions of voltage-gated sodium channel β subunits". Scientific Reports. 6 26618. Bibcode:2016NatSR...626618S. doi:10.1038/srep26618. PMC 4877568. PMID 27216889.
