SR-57227
From Wikipedia, the free encyclopedia
Template:Short description Template:Short description Page Template:Infobox drug/styles.css has no content.
Page Module:Infobox/styles.css has no content.
| Lua error in package.lua at line 80: module 'Module:InfoboxImage/data' not found. | |
| Identifiers | |
|---|---|
| |
| CAS Number | Page Template:Plainlist/styles.css has no content. |
| PubChem CID | Page Template:Plainlist/styles.css has no content. |
| PubChem SID | Page Template:Plainlist/styles.css has no content. |
| IUPHAR/BPS | Page Template:Plainlist/styles.css has no content. |
| DrugBank | Page Template:Plainlist/styles.css has no content. |
| ChemSpider | Page Template:Plainlist/styles.css has no content. |
| UNII | Page Template:Plainlist/styles.css has no content. |
| KEGG | Page Template:Plainlist/styles.css has no content. |
| ChEBI | Page Template:Plainlist/styles.css has no content. |
| ChEMBL | Page Template:Plainlist/styles.css has no content. |
| NIAID ChemDB | Page Template:Plainlist/styles.css has no content. |
| PDB ligand | Page Template:Plainlist/styles.css has no content. |
| CompTox Dashboard (EPA) | Page Template:Plainlist/styles.css has no content. |
| Chemical and physical data | |
| Formula | C10H14ClN3 |
| Molar mass | 211.69 g·mol−1 |
| 3D model (JSmol) | Page Template:Plainlist/styles.css has no content. |
| |
| |
| Data page | |
| Template:Infobox drug/data page link | |
SR-57227 is a potent and selective agonist at the 5HT3 receptor, with high selectivity over other serotonin receptor subtypes and good blood–brain barrier penetration.[1][2][3][4]
References
Page Template:Reflist/styles.css has no content.
- ^ Page Module:Citation/CS1/styles.css has no content.Bachy A, Héaulme M, Giudice A, Michaud JC, Lefevre IA, Souilhac J, et al. (June 1993). "SR 57227A: a potent and selective agonist at central and peripheral 5-HT3 receptors in vitro and in vivo". European Journal of Pharmacology. 237 (2–3): 299–309. doi:10.1016/0014-2999(93)90282-M. PMID 7689975.
- ^ Page Module:Citation/CS1/styles.css has no content.Maksay G, Simonyi M, Bikádi Z (October 2004). "Subunit rotation models activation of serotonin 5-HT3AB receptors by agonists". Journal of Computer-Aided Molecular Design. 18 (10): 651–64. doi:10.1007/s10822-004-6259-0. PMID 15849995. S2CID 10510254.
- ^ Page Module:Citation/CS1/styles.css has no content.Yoo JH, Cho JH, Yu HS, Lee KW, Lee BH, Jeong SM, et al. (November 2006). "Involvement of 5-HT receptors in the development and expression of methamphetamine-induced behavioral sensitization: 5-HT receptor channel and binding study". Journal of Neurochemistry. 99 (3): 976–88. doi:10.1111/j.1471-4159.2006.04137.x. PMID 16942594. S2CID 38685481.
- ^ Page Module:Citation/CS1/styles.css has no content.Li Y, Raaby KF, Sánchez C, Gulinello M (November 2013). "Serotonergic receptor mechanisms underlying antidepressant-like action in the progesterone withdrawal model of hormonally induced depression in rats". Behavioural Brain Research. 256: 520–8. doi:10.1016/j.bbr.2013.09.002. PMID 24016840. S2CID 45617581.
