Sarah Teichmann

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Template:Short description Template:DMCA Script error: No such module "Template wrapper".Script error: No such module "Check for conflicting parameters".Sarah Amalia Teichmann (born 15 April 1975)[1] is a German scientist, the former head of cellular genetics at the Wellcome Sanger Institute[2] and a visiting research group leader at the European Bioinformatics Institute (EMBL-EBI).[3][4] She serves as director of research (equivalent to Professor)[5] in the Cavendish Laboratory,[6] Professor at the University of Cambridge and Cambridge Stem Cell Institute, and is a senior research fellow at Churchill College, Cambridge.[7][8]

Education

Teichmann was educated at the European School, Karlsruhe in Germany from 1981 to 1993 where she completed the European Baccalaureate in 1993.[9] Teichmann went on to study the Natural Sciences Tripos at Trinity College, Cambridge and was awarded a first class Bachelor of Arts degree in 1996. In 1999, she completed her PhD supervised by Cyrus Chothia[10] at the Laboratory of Molecular Biology (LMB) on genome evolution.[11]

Career and research

Following her PhD, Teichmann did postdoctoral research supervised by Janet Thornton at University College London[3] and funded by the Beit Memorial Fellowships for Medical Research. From 2001-2012, she was a Medical Research Council (MRC) Programme Leader, studying patterns in protein interactions and transcriptional regulatory networks.[12][13]

In 2013 Teichmann was appointed a joint position at the Wellcome Trust Sanger Institute and the European Bioinformatics Institute (EMBL-EBI). From 2005 to 2015 she served as a teaching fellow and director of studies at Trinity College, Cambridge. Since 2016 Teichmann has served as the head of Cellular Genetics at the Wellcome Trust Sanger Institute[2] and a visiting research group leader at the EBI.[4]

Teichmann's research[14][15][16][17] investigates gene expression[18][19][20] and protein complex assembly[21] using both wet laboratory and computational biology techniques.[22] In particular her research group:

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...seeks to elucidate the principles of protein structure evolution, higher order protein structure and protein folding, and the principles underlying protein complex formation and organization. We have a longstanding interest in understanding gene expression regulation, and in our wetlab at the Sanger Institute use mouse T helper cells as a model of cell differentiation.[23]

Teichmann's research has been funded by the European Research Council (ERC), the Medical Research Council (MRC), the Biotechnology and Biological Sciences Research Council (BBSRC),[24] the Wellcome Trust, the European Molecular Biology Organization (EMBO), the Framework Programmes for Research and Technological Development and the European Cooperation in Science and Technology (COST).[9]

As of 2015 Teichmann has supervised several PhD students to completion[25][9] including Madan Babu,[26] Varodom Charoensawan[27] Subhajyoti De[28] Jay Han,[29] Sarah Kay Kummerfeld[30][31] Tina Perica,[32] and Jing Su,[33] and several postdoctoral researchers who have gone on to become Principal investigators (PIs).[9][34][35][36]

Awards and honours

Teichmann has won a number of awards. In 2010, she was awarded the Colworth Medal from the Biochemical Society.[37][38] In 2012, Teichman was awarded the Francis Crick Medal and Lecture, membership of the European Molecular Biology Organization (EMBO)[39] and the Lister Prize from the Lister Institute of Preventive Medicine.[40] She won the Suffrage Science award in 2012.[37] In 2015 she was awarded the Michael and Kate Bárány Award for young investigators by the Biophysical Society[41] and the EMBO Gold Medal. Teichmann was elected a Fellow of the Academy of Medical Sciences (FMedSci) in 2015. Her citation on election reads: Page Template:Blockquote/styles.css has no content.

Sarah Teichmann is Research Group Leader at EMBL-European Bioinformatics Institute and has made major contributions to biology over the past 15 years. A fundamental discovery was her work to define key biophysical mechanisms in protein complex assembly, showing that protein complexes assemble via distinct, ordered pathways. She showed that these assembly pathways are conserved in evolution and how they may be predicted from 3D structure. Her databases and computational analysis methods have had a broad and deep impact on the community. She represents a new breed of scientists at the interface between computational and experimental molecular biology.[42]

Teichmann has also been an activist for women's careers in science through enabling scientists in families to advance their careers while working part-time.[43] She chaired a Sex in Science debate at the Wellcome Trust on balancing family life with working in research.[citation needed] Teichmann was elected an ISCB Fellow in 2016 by the International Society for Computational Biology.[44] She was awarded the Mary Lyon Medal by The Genetics Society in 2018.[45]

In 2020, Teichmann was recognised on The Times 'Science Power List' for her work on the Human Cell Atlas[46] and elected a Fellow of the Royal Society.[47]

In 2023 Teichmann was the winner of the Federation of European Biochemical Societies (FEBS) EMBO Women in Science Award.[48]

Personal life

Teichmann has two daughters.[49][50] Teichmann is the co-author of the children's language education novel Teenage Detectives,[51] which she wrote as a teenager together with her mother Dr. Virginia Teichmann, an English-language university lecturer in Karlsruhe.[52] In 2022, Teichmann collaborated in the production of an experimental film Constellations, which was produced by her sister, artist Esther Teichmann, and visual artist Christopher Stewart as an exploration of the Human Cell Atlas. The film was funded by the Wellcome Trust as part of the One Cell at a Time public engagement grant.[53][54]

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content.Teichmann, Sarah (2007). "Sarah Amalia Teichmann PhD MA BA (Hons cantab) CV" (PDF). mrc-lmb.cam.ac.uk. Laboratory of Molecular Biology. Archived from the original (PDF) on 26 February 2013.
  2. ^ a b Page Module:Citation/CS1/styles.css has no content."Dr Sarah Teichmann, FMedSci, Head of Cellular Genetics". Cambridge: sanger.ac.uk. Archived from the original on 15 April 2016.
  3. ^ a b Page Module:Citation/CS1/styles.css has no content.Marx, Vivien (2016). "The Author File: Sarah Teichmann". Nature Methods. 13 (4): 279. doi:10.1038/nmeth.3808. ISSN 1548-7091. PMID 27203785. S2CID 205424792.
  4. ^ a b Cite error: The named reference ebiabout was invoked but never defined (see the help page).
  5. ^ Page Module:Citation/CS1/styles.css has no content.Anon (2013). "Job titles and duties at the University of Cambridge". University of Cambridge. Archived from the original on 3 July 2013.
  6. ^ Page Module:Citation/CS1/styles.css has no content.Anon (2015). "Dr Sarah Teichmann FMedSci". tcm.phy.cam.ac.uk. Cambridge. Archived from the original on 12 September 2015.
  7. ^ Page Module:Citation/CS1/styles.css has no content."People – Churchill College". www.chu.cam.ac.uk.
  8. ^ Page Module:Citation/CS1/styles.css has no content.Dhillon, Paraminder; Teichmann, Sarah A. (2019). "In conversation with Sarah Teichmann". The FEBS Journal. 286 (8): 1445–1450. doi:10.1111/febs.14806. ISSN 1742-464X. PMID 31012289.
  9. ^ a b c d Page Module:Citation/CS1/styles.css has no content.Anon (2015). "Sarah Teichmann: 40th FEBS Congress - The Biochemical Basis of Life - Berlin, Germany". Federation of European Biochemical Societies. Archived from the original on 20 February 2015.
  10. ^ Page Module:Citation/CS1/styles.css has no content.Chothia, C; Gough, J; Vogel, C; Teichmann, S. A. (2003). "Evolution of the protein repertoire". Science. 300 (5626): 1701–3. Bibcode:2003Sci...300.1701C. doi:10.1126/science.1085371. PMID 12805536. S2CID 27681885.
  11. ^ Page Module:Citation/CS1/styles.css has no content.Teichmann, Sarah Amalia (1999). Genome evolution: analysing proteomes with new methods (PhD thesis). University of Cambridge. OCLC 894602472. Template:EThOS.
  12. ^ Page Module:Citation/CS1/styles.css has no content.Babu, M. M.; Luscombe, N. M.; Aravind, L; Gerstein, M; Teichmann, S. A. (2004). "Structure and evolution of transcriptional regulatory networks". Current Opinion in Structural Biology. 14 (3): 283–91. CiteSeerX 10.1.1.471.9692. doi:10.1016/j.sbi.2004.05.004. PMID 15193307.
  13. ^ Page Module:Citation/CS1/styles.css has no content.Luscombe, N. M.; Babu, M. M.; Yu, H; Snyder, M; Teichmann, S. A.; Gerstein, M (2004). "Genomic analysis of regulatory network dynamics reveals large topological changes". Nature. 431 (7006): 308–12. Bibcode:2004Natur.431..308L. doi:10.1038/nature02782. PMID 15372033. S2CID 4391278.
  14. ^ {{ACM Portal}} template missing ID and not present in Wikidata.
  15. ^ {{DBLP}} template missing ID and not present in Wikidata.
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  17. ^ Sarah Teichmann publications from Europe PubMed CentralTemplate:EditAtWikidata
  18. ^ Page Module:Citation/CS1/styles.css has no content.Carninci, P; Kasukawa, T; Katayama, S; Gough, J; Frith, M. C.; Maeda, N; Oyama, R; Ravasi, T; Lenhard, B; Wells, C; Kodzius, R; Shimokawa, K; Bajic, V. B.; Brenner, S. E.; Batalov, S; Forrest, A. R.; Zavolan, M; Davis, M. J.; Wilming, L. G.; Aidinis, V; Allen, J. E.; Ambesi-Impiombato, A; Apweiler, R; Aturaliya, R. N.; Bailey, T. L.; Bansal, M; Baxter, L; Beisel, K. W.; Bersano, T; et al. (2005). "The transcriptional landscape of the mammalian genome". Science. 309 (5740): 1559–63. Bibcode:2005Sci...309.1559F. doi:10.1126/science.1112014. PMID 16141072. S2CID 8712839.
  19. ^ Page Module:Citation/CS1/styles.css has no content.Drosophila 12 Genomes Consortium; Clark, A. G.; Eisen, M. B.; Smith, D. R.; Bergman, C. M.; Oliver, B; Markow, T. A.; Kaufman, T. C.; Kellis, M; Gelbart, W; Iyer, V. N.; Pollard, D. A.; Sackton, T. B.; Larracuente, A. M.; Singh, N. D.; Abad, J. P.; Abt, D. N.; Adryan, B; Aguade, M; Akashi, H; Anderson, W. W.; Aquadro, C. F.; Ardell, D. H.; Arguello, R; Artieri, C. G.; Barbash, D. A.; Barker, D; Barsanti, P; Batterham, P; et al. (2007). "Evolution of genes and genomes on the Drosophila phylogeny". Nature. 450 (7167): 203–18. Bibcode:2007Natur.450..203C. doi:10.1038/nature06341. PMID 17994087.
  20. ^ Page Module:Citation/CS1/styles.css has no content.Wilson, D; Charoensawan, V; Kummerfeld, S. K.; Teichmann, S. A. (2008). "DBD--taxonomically broad transcription factor predictions: New content and functionality". Nucleic Acids Research. 36 (Database issue): D88–92. doi:10.1093/nar/gkm964. PMC 2238844. PMID 18073188.
  21. ^ Page Module:Citation/CS1/styles.css has no content.Levy, E. D.; Teichmann, S (2013). "Structural, Evolutionary, and Assembly Principles of Protein Oligomerization". Oligomerization in Health and Disease. Progress in Molecular Biology and Translational Science. Vol. 117. pp. 25–51. doi:10.1016/B978-0-12-386931-9.00002-7. ISBN 978-0-12-386931-9. PMID 23663964.
  22. ^ Page Module:Citation/CS1/styles.css has no content.Perica, T; Kondo, Y; Tiwari, S. P.; McLaughlin, S. H.; Kemplen, K. R.; Zhang, X; Steward, A; Reuter, N; Clarke, J; Teichmann, S. A. (2014). "Evolution of oligomeric state through allosteric pathways that mimic ligand binding". Science. 346 (6216) 1254346. doi:10.1126/science.1254346. PMC 4337988. PMID 25525255.
  23. ^ Page Module:Citation/CS1/styles.css has no content."Teichmann group Research EMBL-EBI". European Bioinformatics Institute. 2013. Archived from the original on 2 April 2013.
  24. ^ Page Module:Citation/CS1/styles.css has no content.Anon (2015). "UK Government research grants awarded to Sarah Teichmann". Research Councils UK. Archived from the original on 3 March 2015.
  25. ^ Page Module:Citation/CS1/styles.css has no content.Teichmann, Sarah (2015). "Alumni from Sarah Teichmann's Group". European Bioinformatics Institute.{{cite web}}: CS1 maint: deprecated archival service (link)
  26. ^ Cite error: The named reference babuphd was invoked but never defined (see the help page).
  27. ^ Page Module:Citation/CS1/styles.css has no content.Charoensawan, Varodom (2011). Evolution and dynamics of transcription factors and gene expression patterns. ethos.bl.uk (PhD thesis). University of Cambridge. OCLC 890150091.
  28. ^ Page Module:Citation/CS1/styles.css has no content.De, Subhajyoti (2008). Human genome evolution: investigating protein divergence, polymorphisms and genomic neighbourhood. ethos.bl.uk (PhD thesis). University of Cambridge. OCLC 890154864.
  29. ^ Page Module:Citation/CS1/styles.css has no content.Han, Jay (2007). Structure, function and evolution of protein-protein interactions (PhD thesis). University of Cambridge.
  30. ^ Page Module:Citation/CS1/styles.css has no content.Kummerfeld, Sarah Kay (2006). Towards understanding the protein universe: genome-scale studies of evolution and gene regulation. ethos.bl.uk (PhD thesis). University of Cambridge.
  31. ^ Page Module:Citation/CS1/styles.css has no content.Levy, Emmanuel Doram (2008). Classification, evolution, and assembly of protein complexes. ethos.bl.uk (PhD thesis). University of Cambridge.
  32. ^ Page Module:Citation/CS1/styles.css has no content.Perica, Tina (2013). Evolutionary and structural dynamics of protein complexes (PhD thesis). University of Cambridge. OCLC 890148231.
  33. ^ Page Module:Citation/CS1/styles.css has no content.Su, Jing (2012). Computational prediction of regulatory elements (PhD thesis). University of Cambridge.
  34. ^ Page Module:Citation/CS1/styles.css has no content.Adryan, B; Teichmann, S. A. (2010). "The developmental expression dynamics of Drosophila melanogaster transcription factors". Genome Biology. 11 (4): R40. doi:10.1186/gb-2010-11-4-r40. PMC 2884543. PMID 20384991.
  35. ^ Page Module:Citation/CS1/styles.css has no content.Gsponer, J; Futschik, M. E.; Teichmann, S. A.; Babu, M. M. (2008). "Tight regulation of unstructured proteins: From transcript synthesis to protein degradation". Science. 322 (5906): 1365–8. Bibcode:2008Sci...322.1365G. doi:10.1126/science.1163581. PMC 2803065. PMID 19039133.
  36. ^ Page Module:Citation/CS1/styles.css has no content.Hebenstreit, D; Gu, M; Haider, S; Turner, D. J.; Liò, P; Teichmann, S. A. (2011). "EpiChIP: Gene-by-gene quantification of epigenetic modification levels". Nucleic Acids Research. 39 (5): e27. doi:10.1093/nar/gkq1226. PMC 3061070. PMID 21131282.
  37. ^ a b Page Module:Citation/CS1/styles.css has no content.Anon (2012). "Honour and heirloom for Sarah Teichmann". Laboratory of Molecular Biology. Archived from the original on 3 March 2015.
  38. ^ Page Module:Citation/CS1/styles.css has no content.Anon (2015). "Women at Cambridge: Sarah Amalia Teichmann". University of Cambridge. Archived from the original on 20 February 2015.
  39. ^ Cite error: The named reference embom was invoked but never defined (see the help page).
  40. ^ Cite error: The named reference lister was invoked but never defined (see the help page).
  41. ^ Page Module:Citation/CS1/styles.css has no content."Biophysical Society Names 2015 Award Recipients" (PDF). Biophysical Society. Archived from the original (PDF) on 4 October 2014. Retrieved 8 March 2015.
  42. ^ Page Module:Citation/CS1/styles.css has no content.Anon (2015). "Dr Sarah Teichmann FMedSci". acmedsci.ac.uk. London: Academy of Medical Sciences. Archived from the original on 6 July 2015.
  43. ^ Page Module:Citation/CS1/styles.css has no content.Gaskell & Kostic (2015). "The Unstoppable Sarah Teichmann on Programing, Motherhood, and Protein Complex Assembly:The Female Scientist". Cell. Archived from the original on 2 April 2016. Retrieved 25 November 2015.
  44. ^ Page Module:Citation/CS1/styles.css has no content.Anon (2017). "ISCB Fellows". iscb.org. International Society for Computational Biology. Archived from the original on 20 March 2017.
  45. ^ Page Module:Citation/CS1/styles.css has no content."Mary Lyon Medal 2018 — Sarah Teichmann". The Genetics Society. Retrieved 6 May 2026.
  46. ^ Page Module:Citation/CS1/styles.css has no content.Franklin-Wallis, Oliver (23 May 2020). "From pandemics to cancer: the science power list". The Times. ISSN 0140-0460. Retrieved 26 May 2020.
  47. ^ Page Module:Citation/CS1/styles.css has no content."Sarah Teichmann". Royal Society. Retrieved 20 September 2020.
  48. ^ Page Module:Citation/CS1/styles.css has no content."FEBS | EMBO Women in Science Award - FEBS". 26 August 2022. Retrieved 4 January 2024.
  49. ^ Cite error: The named reference 4am was invoked but never defined (see the help page).
  50. ^ Page Module:Citation/CS1/styles.css has no content.Pain, Elisabeth (2015). "Harnessing computer power to understand biology". Science. doi:10.1126/science.caredit.a1500172.
  51. ^ Page Module:Citation/CS1/styles.css has no content.Teichmann, Sarah; Teichmann, Virginia (1991). Cornelsen English Library - Fiction: 8. Schuljahr, Stufe 1 - Teenage Detectives: Textheft. Mit Aufgaben und Activities. Germany: Cornelsen Verlag. ISBN 978-3-464-05336-2.
  52. ^ Page Module:Citation/CS1/styles.css has no content.Anon. "The Honeycomb: Dr. Virginia Teichmann: Word Lover" (PDF). expat-karlsruhe.com. Retrieved 7 December 2015.
  53. ^ Page Module:Citation/CS1/styles.css has no content."Constellations – One Cell at a Time". www.onecellatatime.org. Retrieved 28 March 2025.
  54. ^ Page Module:Citation/CS1/styles.css has no content."Tank Magazine". Tank Magazine. Retrieved 28 March 2025.

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