TAOK2
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Template:Short description An Error has occurred retrieving Wikidata item for infobox Serine/threonine-protein kinase TAO2 is an enzyme that in humans is encoded by the TAOK2 gene.[1][2][3]
Interactions
TAOK2 has been shown to interact with MAP2K6[4] and MAP2K3.[4]
References
Page Template:Reflist/styles.css has no content.
- ^ Page Module:Citation/CS1/styles.css has no content.Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, et al. (December 1998). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (6): 355–364. doi:10.1093/dnares/5.6.355. PMID 10048485.
- ^ Page Module:Citation/CS1/styles.css has no content.Hutchison M, Berman KS, Cobb MH (October 1998). "Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades". The Journal of Biological Chemistry. 273 (44): 28625–28632. doi:10.1074/jbc.273.44.28625. PMID 9786855.
- ^ Page Module:Citation/CS1/styles.css has no content."Entrez Gene: TAOK2 TAO kinase 2".
- ^ a b Page Module:Citation/CS1/styles.css has no content.Chen Z, Cobb MH (May 2001). "Regulation of stress-responsive mitogen-activated protein (MAP) kinase pathways by TAO2". The Journal of Biological Chemistry. 276 (19): 16070–16075. doi:10.1074/jbc.M100681200. PMID 11279118.
Further reading
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- Page Module:Citation/CS1/styles.css has no content.Chen Z, Hutchison M, Cobb MH (October 1999). "Isolation of the protein kinase TAO2 and identification of its mitogen-activated protein kinase/extracellular signal-regulated kinase kinase binding domain". The Journal of Biological Chemistry. 274 (40): 28803–28807. doi:10.1074/jbc.274.40.28803. PMID 10497253.
- Page Module:Citation/CS1/styles.css has no content.Moore TM, Garg R, Johnson C, Coptcoat MJ, Ridley AJ, Morris JD (February 2000). "PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organization". The Journal of Biological Chemistry. 275 (6): 4311–4322. doi:10.1074/jbc.275.6.4311. PMID 10660600.
- Page Module:Citation/CS1/styles.css has no content.Nakayama M, Kikuno R, Ohara O (November 2002). "Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs". Genome Research. 12 (11): 1773–1784. doi:10.1101/gr.406902. PMC 187542. PMID 12421765.
- Page Module:Citation/CS1/styles.css has no content.Mitsopoulos C, Zihni C, Garg R, Ridley AJ, Morris JD (May 2003). "The prostate-derived sterile 20-like kinase (PSK) regulates microtubule organization and stability". The Journal of Biological Chemistry. 278 (20): 18085–18091. doi:10.1074/jbc.M213064200. PMID 12639963.
- Page Module:Citation/CS1/styles.css has no content.Chen Z, Raman M, Chen L, Lee SF, Gilman AG, Cobb MH (June 2003). "TAO (thousand-and-one amino acid) protein kinases mediate signaling from carbachol to p38 mitogen-activated protein kinase and ternary complex factors". The Journal of Biological Chemistry. 278 (25): 22278–22283. doi:10.1074/jbc.M301173200. PMID 12665513.
- Page Module:Citation/CS1/styles.css has no content.Yustein JT, Xia L, Kahlenburg JM, Robinson D, Templeton D, Kung HJ (September 2003). "Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38". Oncogene. 22 (40): 6129–6141. doi:10.1038/sj.onc.1206605. PMID 13679851.
- Page Module:Citation/CS1/styles.css has no content.Huangfu WC, Omori E, Akira S, Matsumoto K, Ninomiya-Tsuji J (September 2006). "Osmotic stress activates the TAK1-JNK pathway while blocking TAK1-mediated NF-kappaB activation: TAO2 regulates TAK1 pathways". The Journal of Biological Chemistry. 281 (39): 28802–28810. doi:10.1074/jbc.M603627200. PMC 1797068. PMID 16893890.
- Page Module:Citation/CS1/styles.css has no content.Zihni C, Mitsopoulos C, Tavares IA, Baum B, Ridley AJ, Morris JD (March 2007). "Prostate-derived sterile 20-like kinase 1-alpha induces apoptosis. JNK- and caspase-dependent nuclear localization is a requirement for membrane blebbing". The Journal of Biological Chemistry. 282 (9): 6484–6493. doi:10.1074/jbc.M608336200. PMID 17158878.
- Page Module:Citation/CS1/styles.css has no content.Wojtala RL, Tavares IA, Morton PE, Valderrama F, Thomas NS, Morris JD (August 2011). "Prostate-derived sterile 20-like kinases (PSKs/TAOKs) are activated in mitosis and contribute to mitotic cell rounding and spindle positioning". The Journal of Biological Chemistry. 286 (34): 30161–30170. doi:10.1074/jbc.M111.228320. PMC 3191055. PMID 21705329.
- Page Module:Citation/CS1/styles.css has no content.de Anda FC, Rosario AL, Durak O, Tran T, Gräff J, Meletis K, et al. (June 2012). "Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex". Nature Neuroscience. 15 (7): 1022–1031. doi:10.1038/nn.3141. PMC 4017029. PMID 22683681.
- Page Module:Citation/CS1/styles.css has no content.Tavares IA, Touma D, Lynham S, Troakes C, Schober M, Causevic M, et al. (May 2013). "Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease". The Journal of Biological Chemistry. 288 (21): 15418–15429. doi:10.1074/jbc.M112.448183. PMC 3663559. PMID 23585562.
- Page Module:Citation/CS1/styles.css has no content.Koo CY, Giacomini C, Reyes-Corral M, Olmos Y, Tavares IA, Marson CM, et al. (November 2017). "Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells". Molecular Cancer Therapeutics. 16 (11): 2410–2421. doi:10.1158/1535-7163.MCT-17-0077. PMID 28830982.
- Page Module:Citation/CS1/styles.css has no content.Richter M, Murtaza N, Scharrenberg R, White SH, Johanns O, Walker S, et al. (September 2019). "Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling". Molecular Psychiatry. 24 (9): 1329–1350. doi:10.1038/s41380-018-0025-5. PMC 6756231. PMID 29467497.
- Page Module:Citation/CS1/styles.css has no content.Giacomini C, Koo CY, Yankova N, Tavares IA, Wray S, Noble W, et al. (May 2018). "A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies". Acta Neuropathologica Communications. 6 (1): 37. doi:10.1186/s40478-018-0539-8. PMC 5937037. PMID 29730992.
- Page Module:Citation/CS1/styles.css has no content.Scharrenberg R, Richter M, Johanns O, Meka DP, Rücker T, Murtaza N, et al. (September 2022). "TAOK2 rescues autism-linked developmental deficits in a 16p11.2 microdeletion mouse model". Molecular Psychiatry. 27 (11): 4707–4721. doi:10.1038/s41380-022-01785-3. PMC 9734055. PMID 36123424. S2CID 252382956.
