Timepidium bromide

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Timepidium bromide
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Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		SC, IM, IV
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Legal status
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  • In general: ℞ (Prescription only)
Identifiers
  • 3-(di-2-thienylmethylene)-5-methoxy-1,1-dimethylpiperidinium bromide
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Chemical and physical data
FormulaC17H22BrNOS2
Molar mass400.39 g·mol−1
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  • C[N+]1(CC(CC(=C(C2=CC=CS2)C3=CC=CS3)C1)OC)C.[Br-]
  • InChI=1S/C17H22NOS2.BrH/c1-18(2)11-13(10-14(12-18)19-3)17(15-6-4-8-20-15)16-7-5-9-21-16;/h4-9,14H,10-12H2,1-3H3;1H/q+1;/p-1 ☒N
  • Key:QTSXMEPZSHLZFF-UHFFFAOYSA-M ☒N
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Timepidium bromide (INN) is an anticholinergic. It is used in the symptomatic treatment of visceral spasms.[1] It is also used to relieve pain associated with various gastrointestinal disorders.[2] The quaternary nitrogen prevents it from crossing the blood brain barrier, so it is peripherally acting with no central side effects.

The same compound sans the quaternary methyl group and the methoxy ether is called tipepidine.[3]

References

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  1. ^ Page Module:Citation/CS1/styles.css has no content."Timepidium bromide: Indication, Dosage, Side Effect, Precaution | MIMS Malaysia". www.mims.com. Retrieved 2021-07-05.
  2. ^ Page Module:Citation/CS1/styles.css has no content."Timepidium Bromide Tablets 30mg SAWAI 100 Tablets｜Natural Pharmacy". www.mimaki-family-japan.com. Archived from the original on 2025-01-25. Retrieved 2021-07-05.
  3. ^ Page Module:Citation/CS1/styles.css has no content.Shah R, Verma PK (December 2018). "Therapeutic importance of synthetic thiophene". Chemistry Central Journal. 12 (1) 137. doi:10.1186/s13065-018-0511-5. PMC 6768136. PMID 30564984.

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