WNT2
From Wikipedia, the free encyclopedia
Template:Short description An Error has occurred retrieving Wikidata item for infobox Wingless-type MMTV integration site family, member 2, also known as WNT2, is a human gene.[1][2]
This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes that encode secreted signaling proteins involved in the Wnt signaling pathway. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene.[1]
References
Page Template:Reflist/styles.css has no content.
- ^ a b Page Module:Citation/CS1/styles.css has no content."Entrez Gene: WNT2 wingless-type MMTV integration site family, member 2".
- ^ Page Module:Citation/CS1/styles.css has no content.Wainwright BJ, Scambler PJ, Stanier P, Watson EK, Bell G, Wicking C, Estivill X, Courtney M, Boue A, Pedersen PS (June 1988). "Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless". EMBO J. 7 (6): 1743–8. doi:10.1002/j.1460-2075.1988.tb03003.x. PMC 457162. PMID 2971536.
Further reading
Page Template:Refbegin/styles.css has no content.
- Page Module:Citation/CS1/styles.css has no content.Katoh M (2003). "WNT2 and human gastrointestinal cancer (review)". Int. J. Mol. Med. 12 (5): 811–6. doi:10.3892/ijmm.12.5.811. PMID 14533014.
- Page Module:Citation/CS1/styles.css has no content.Li J, Nguyen L, Gleason C, et al. (2004). "Lack of evidence for an association between WNT2 and RELN polymorphisms and autism". Am. J. Med. Genet. B Neuropsychiatr. Genet. 126B (1): 51–7. doi:10.1002/ajmg.b.20122. PMID 15048648. S2CID 19378694.
- Page Module:Citation/CS1/styles.css has no content.Pu P, Zhang Z, Kang C, et al. (2009). "Downregulation of Wnt2 and beta-catenin by siRNA suppresses malignant glioma cell growth". Cancer Gene Ther. 16 (4): 351–61. doi:10.1038/cgt.2008.78. PMID 18949017.
- Page Module:Citation/CS1/styles.css has no content.Kodo K, Nishizawa T, Furutani M, et al. (2009). "GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling". Proc. Natl. Acad. Sci. U.S.A. 106 (33): 13933–8. Bibcode:2009PNAS..10613933K. doi:10.1073/pnas.0904744106. PMC 2728998. PMID 19666519.
- Page Module:Citation/CS1/styles.css has no content.Clément G, Braunschweig R, Pasquier N, et al. (2006). "Alterations of the Wnt signaling pathway during the neoplastic progression of Barrett's esophagus". Oncogene. 25 (21): 3084–92. doi:10.1038/sj.onc.1209338. PMID 16407829.
- Page Module:Citation/CS1/styles.css has no content.Park JK, Song JH, He TC, et al. (2009). "Overexpression of Wnt-2 in colorectal cancers". Neoplasma. 56 (2): 119–23. doi:10.4149/neo_2009_02_119. PMID 19239325.
- Page Module:Citation/CS1/styles.css has no content.Flahaut M, Meier R, Coulon A, et al. (2009). "The Wnt receptor FZD1 mediates chemoresistance in neuroblastoma through activation of the Wnt/beta-catenin pathway". Oncogene. 28 (23): 2245–56. doi:10.1038/onc.2009.80. PMID 19421142. S2CID 205531490.
- Page Module:Citation/CS1/styles.css has no content.Liu ZL, Li Y, Kong QY, et al. (2008). "Immunohistochemical profiling of Wnt, NF-kappaB, Stat3 and Notch signaling in human epidermal tumors". J. Dermatol. Sci. 52 (2): 133–6. doi:10.1016/j.jdermsci.2008.06.011. PMID 18703315.
- Page Module:Citation/CS1/styles.css has no content.Kloth JN, Fleuren GJ, Oosting J, et al. (2005). "Substantial changes in gene expression of Wnt, MAPK and TNFalpha pathways induced by TGF-beta1 in cervical cancer cell lines". Carcinogenesis. 26 (9): 1493–502. doi:10.1093/carcin/bgi110. PMID 15878915.
- Page Module:Citation/CS1/styles.css has no content.Mazieres J, You L, He B, et al. (2005). "Wnt2 as a new therapeutic target in malignant pleural mesothelioma". Int. J. Cancer. 117 (2): 326–32. doi:10.1002/ijc.21160. PMID 15900580. S2CID 23153113.
- Page Module:Citation/CS1/styles.css has no content.Wang HX, Tekpetey FR, Kidder GM (2009). "Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells". Mol. Hum. Reprod. 15 (1): 11–7. doi:10.1093/molehr/gan070. PMID 19038973.
- Page Module:Citation/CS1/styles.css has no content.Han JC, Zhang KL, Chen XY, et al. (2007). "Expression of seven gastric cancer-associated genes and its relevance for Wnt, NF-kappaB and Stat3 signaling". APMIS. 115 (12): 1331–43. doi:10.1111/j.1600-0643.2007.00695.x. PMID 18184402. S2CID 42263784.
- Page Module:Citation/CS1/styles.css has no content.Planutis K, Planutiene M, Moyer MP, et al. (2007). "Regulation of norrin receptor frizzled-4 by Wnt2 in colon-derived cells". BMC Cell Biol. 8: 12. doi:10.1186/1471-2121-8-12. PMC 1847812. PMID 17386109.
- Page Module:Citation/CS1/styles.css has no content.Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Page Module:Citation/CS1/styles.css has no content.Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Page Module:Citation/CS1/styles.css has no content.Cheng XX, Wang ZC, Chen XY, et al. (2005). "Frequent loss of membranous E-cadherin in gastric cancers: A cross-talk with Wnt in determining the fate of beta-catenin". Clin. Exp. Metastasis. 22 (1): 85–93. doi:10.1007/s10585-005-4578-8. PMID 16132582. S2CID 20775755.
- Page Module:Citation/CS1/styles.css has no content.Shi Y, He B, Kuchenbecker KM, et al. (2007). "Inhibition of Wnt-2 and galectin-3 synergistically destabilizes beta-catenin and induces apoptosis in human colorectal cancer cells". Int. J. Cancer. 121 (6): 1175–81. doi:10.1002/ijc.22848. PMID 17534895. S2CID 23180009.
- Page Module:Citation/CS1/styles.css has no content.Cheng XX, Wang ZC, Chen XY, et al. (2005). "Correlation of Wnt-2 expression and beta-catenin intracellular accumulation in Chinese gastric cancers: relevance with tumour dissemination". Cancer Lett. 223 (2): 339–47. doi:10.1016/j.canlet.2004.11.013. PMID 15896469.
- Page Module:Citation/CS1/styles.css has no content.Ma XR, Edmund Sim UH, Pauline B, et al. (2008). "Overexpression of WNT2 and TSG101 genes in colorectal carcinoma". Tropical Biomedicine. 25 (1): 46–57. PMID 18600204.
- Page Module:Citation/CS1/styles.css has no content.de Krom M, Staal WG, Ophoff RA, et al. (2009). "A common variant in DRD3 receptor is associated with autism spectrum disorder". Biol. Psychiatry. 65 (7): 625–30. doi:10.1016/j.biopsych.2008.09.035. PMID 19058789. S2CID 11545813.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Lua error in package.lua at line 80: module 'Module:Navbox/configuration' not found.
